Date published: 2026-4-28

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Myristic Acid alkyne (CAS 82909-47-5)

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CAS Number:
82909-47-5
Molecular Weight:
224.3
Molecular Formula:
C14H24O2
Supplemental Information:
This is classified as a Dangerous Good for transport and may be subject to additional shipping charges.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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Myristic Acid Alkyne, bearing the CAS number 82909-47-5, is an alkyne-functionalized derivative of myristic acid, a 14-carbon saturated fatty acid. This chemical is particularly noted for its incorporation of a terminal alkyne group, which significantly enhances its utility in various research domains, especially in the field of organic synthesis and material science. The alkyne group in myristic acid alkyne introduces a reactive site for click chemistry reactions, a popular and efficient method for covalently linking molecules in a modular fashion using azides and alkynes. This functionality has rendered myristic acid alkyne a valuable tool for constructing complex molecular architectures through bioconjugation techniques. Researchers utilize this compound in the design and synthesis of lipid analogs, where the alkyne moiety can be strategically employed to tag or anchor molecules to cellular membranes or other lipid-containing structures for studying lipid dynamics and interactions. Additionally, myristic acid alkyne has found applications in the development of surface coatings and as a precursor for polymer synthesis, where the ability to form robust covalent bonds is advantageous for creating stable, functional materials. The use of myristic acid alkyne in these contexts provides insights into lipid behavior and aids in the advancement of materials with specific chemical and physical properties.


Myristic Acid alkyne (CAS 82909-47-5) References

  1. EGR2 phosphatase regulates OST1 kinase activity and freezing tolerance in Arabidopsis.  |  Ding, Y., et al. 2019. EMBO J. 38: PMID: 30429206
  2. Fatty acids impact sarcomere integrity through myristoylation and ER homeostasis.  |  Tang, H., et al. 2021. Cell Rep. 36: 109539. PMID: 34407398
  3. A metabolic labeling protocol to enrich myristoylated proteins from Caenorhabditis elegans.  |  Gong, X., et al. 2021. STAR Protoc. 2: 101013. PMID: 34917984
  4. Binding Affinity Determines Substrate Specificity and Enables Discovery of Substrates for N-Myristoyltransferases.  |  Su, D., et al. 2021. ACS Catal. 11: 14877-14883. PMID: 34956690
  5. The BASP1 transcriptional corepressor modifies chromatin through lipid-dependent and lipid-independent mechanisms.  |  Moorhouse, AJ., et al. 2022. iScience. 25: 104796. PMID: 35982799
  6. Inhibition of vaccinia virus L1 N-myristoylation by the host N-myristoyltransferase inhibitor IMP-1088 generates non-infectious virions defective in cell entry.  |  Priyamvada, L., et al. 2022. PLoS Pathog. 18: e1010662. PMID: 36215331
  7. Myristic acid as a checkpoint to regulate STING-dependent autophagy and interferon responses by promoting N-myristoylation.  |  Jia, M., et al. 2023. Nat Commun. 14: 660. PMID: 36750575
  8. HDAC11 inhibition triggers bimodal thermogenic pathways to circumvent adipocyte catecholamine resistance.  |  Robinson, EL., et al. 2023. J Clin Invest. 133: PMID: 37607030
  9. Bi-allelic ACBD6 variants lead to a neurodevelopmental syndrome with progressive and complex movement disorders.  |  Kaiyrzhanov, R., et al. 2024. Brain. 147: 1436-1456. PMID: 37951597

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Myristic Acid alkyne, 100 µg

sc-295507
100 µg
$86.00

Myristic Acid alkyne, 500 µg

sc-295507A
500 µg
$390.00