Molecular structure of Muramic acid, CAS Number: 1114-41-6
Muramic acid (CAS 1114-41-6)
Alternate Names:
2-Amino-3-O-(1-carboxyethyl)-2-deoxy-D-glucose
Application:
Muramic acid is a component in many Gram-positive bacterial cell wall
CAS Number:
1114-41-6
Purity:
≥95%
Molecular Weight:
251.23
Molecular Formula:
C9H17NO7
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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SDS & Certificate of Analysis
Muramic acid a significant component of the peptidoglycan layer found in bacterial cell walls. It serves as a key structural unit that contributes to the strength and rigidity of the cell wall, providing protection and shape to bacterial cells. It is often a focus in the study of bacterial cell wall synthesis and integrity, as well as in the investigation of the mechanisms by which bacteria resist or succumb to the action of certain agents that target cell wall synthesis. Muramic acid also play a role in the development of diagnostic tools, as its presence can be indicative of bacterial biomass in different environments or samples.
Muramic acid (CAS 1114-41-6) References
- Failure To detect muramic acid in normal rat tissues but detection in cerebrospinal fluids from patients with Pneumococcal meningitis. | Kozar, MP., et al. 2000. Infect Immun. 68: 4688-98. PMID: 10899874
- Muramic Acid measurements for bacterial investigations in marine environments by high-pressure liquid chromatography. | Mimura, T. and Romano, JC. 1985. Appl Environ Microbiol. 50: 229-37. PMID: 16346848
- Legume lectins interact with muramic acid and N-acetylmuramic acid. | Ayouba, A., et al. 1991. FEBS Lett. 289: 102-4. PMID: 1893996
- Muramic acid, endotoxin, 3-hydroxy fatty acids, and ergosterol content explain monocyte and epithelial cell inflammatory responses to agricultural dusts. | Poole, JA., et al. 2010. J Toxicol Environ Health A. 73: 684-700. PMID: 20391112
- Investigation of the molecular ion structure for aldononitrile acetate derivatized muramic acid. | Liang, C., et al. 2011. J Microbiol Methods. 86: 224-30. PMID: 21621564
- GC-based detection of aldononitrile acetate derivatized glucosamine and muramic acid for microbial residue determination in soil. | Liang, C., et al. 2012. J Vis Exp. e3767. PMID: 22643738
- Muramic acid is not detectable in Chlamydia psittaci or Chlamydia trachomatis by gas chromatography-mass spectrometry. | Fox, A., et al. 1990. Infect Immun. 58: 835-7. PMID: 2307520
- Endotoxin, ergosterol, muramic acid and fungal DNA in dust from schools in Johor Bahru, Malaysia--Associations with rhinitis and sick building syndrome (SBS) in junior high school students. | Norbäck, D., et al. 2016. Sci Total Environ. 545-546: 95-103. PMID: 26745297
- Quantitation of amino sugar stereoisomer and muramic acid biomarkers by hydrophilic interaction liquid chromatography-mass spectrometry. | VandenBoer, TC., et al. 2020. J Chromatogr A. 1618: 460843. PMID: 31928774
- Development of analytical methods for the determination of 3-hydroxy fatty acids and muramic acid as bacterial markers in airborne particles and settled dust. | Hong, G., et al. 2023. J Chromatogr A. 1688: 463708. PMID: 36528898
- Muramic acid detection in mammalian tissues by gas-liquid chromatography-mass spectrometry. | Fox, A., et al. 1980. Infect Immun. 29: 526-31. PMID: 7011978
- Muramic acid in peripheral blood leukocytes of healthy human subjects. | Lehtonen, L., et al. 1995. J Infect Dis. 171: 1060-4. PMID: 7706791
- Detection of muramic acid in a carbohydrate fraction of human spleen. | Hoijer, MA., et al. 1995. Infect Immun. 63: 1652-7. PMID: 7729869
- Muramic acid as a measure of microbial biomass in estuarine and marine samples. | King, JD. and White, DC. 1977. Appl Environ Microbiol. 33: 777-83. PMID: 869528
- Absolute identification of muramic acid, at trace levels, in human septic synovial fluids in vivo and absence in aseptic fluids. | Fox, A., et al. 1996. Infect Immun. 64: 3911-5. PMID: 8751949
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Muramic acid, 5 mg | sc-218893 | 5 mg | $140.00 | |||
Muramic acid, 25 mg | sc-218893A | 25 mg | $465.00 |