MRP2 Antibody (M2I-4): sc-59609
- MRP2 Antibody (M2I-4) is a mouse monoclonal IgG1 MRP2 antibody, cited in 4 publications, provided at 500 µl supernatant
- raised against an internal region of MRP2 of human origin
- recommended for detection of MRP2 of human origin by WB, IP and IF; non cross-reactive with MDR1, MRP1, MRP3 or MRP5
- At present, we have not yet completed the identification of the preferred secondary detection reagent(s) for MRP2 Antibody (M2I-4). This work is in progress.
MRP2 Antibody (M2I-4) is a mouse monoclonal IgG1 antibody that detects MRP2 protein of human origin by western blotting (WB), immunoprecipitation (IP), and immunofluorescence (IF). Anti-MRP2 antibody (M2I-4) is available as a non-conjugated format, specifically targeting the canalicular multispecific organic anion transporter, which plays a crucial role in the excretion of various endogenous and exogenous compounds, including drugs and toxins, from hepatocytes into bile. MRP2 (M2I-4) antibody targets a protein vital for maintaining cellular homeostasis and protecting the liver from potential damage caused by harmful substances. MRP2 monoclonal antibody (M2I-4) recognizes a protein predominantly localized to the apical membrane of hepatocytes, where MRP2 facilitates the transport of organic anions, thereby influencing drug metabolism and resistance in cancer therapy. MRP2 expression is constitutively high in normal liver cells, and MRP2 activity can significantly impact the pharmacokinetics of therapeutic agents, making MRP2 an important target for research in drug development and toxicology. Understanding MRP2 dynamics and interactions with various substrates can provide insights into multidrug resistance mechanisms in cancer and the overall detoxification processes in the liver.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
MRP2 Antibody (M2I-4) | sc-59609 | 500 µl supernatant | $316.00 |