Date published: 2026-4-24

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Monoethyl Phthalate (CAS 2306-33-4)

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Datasheets
Alternate Names:
Ethyl 2-Carboxybenzoate; Phthalic Acid Monoethyl Ester; 1,2-Benzenedicarboxylic Acid Monoethyl Ester
CAS Number:
2306-33-4
Molecular Weight:
194.18
Molecular Formula:
C10H10O4
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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Monoethyl Phthalate (MEP) is a phthalic acid monoester resulting from the condensation of one of the carboxy groups of phthalic acid with ethanol. It is a derivative of benzoic acid and one of the metabolites of diethyl phthalate (DEP). It has been detected in multiple biofluids, such as urine and saliva therefore, it serves as a biomarker for exposure to DEP. Phthalate esters like Monoethyl Phthalate are used as plasticizers in various industrial applications. Phthalates, including DEP and its metabolites like Monoethyl Phthalate, have been studied for their potential as endocrine-disrupting chemicals that could interfere with hormone systems.


Monoethyl Phthalate (CAS 2306-33-4) References

  1. Low dose monoethyl phthalate (MEP) exposure triggers proliferation by activating PDX-1 at 1.1B4 human pancreatic beta cells.  |  Güven, C., et al. 2016. Food Chem Toxicol. 93: 41-50. PMID: 27133914
  2. Phthalate Metabolites, Consumer Habits and Health Effects.  |  Wallner, P., et al. 2016. Int J Environ Res Public Health. 13: PMID: 27428989
  3. Association of phthalates, parabens and phenols found in personal care products with pubertal timing in girls and boys.  |  Harley, KG., et al. 2019. Hum Reprod. 34: 109-117. PMID: 30517665
  4. Simultaneous determination of diethyl phthalate and its major metabolite, monoethyl phthalate, in rat plasma, urine, and various tissues collected from a toxicokinetic study by ultrahigh performance liquid chromatography-tandem mass spectrometry.  |  Jeong, SH., et al. 2019. J Pharm Biomed Anal. 173: 108-119. PMID: 31125947
  5. Association between Phthalate Metabolites and Risk of Endometriosis: A Meta-Analysis.  |  Cai, W., et al. 2019. Int J Environ Res Public Health. 16: PMID: 31574938
  6. Palladium-Catalyzed Carboxylate-Assisted Ethoxycarboxylation of Aromatic Acids To Synthesize Monoethyl Phthalate Derivatives with Ethyl Bromodifluoroacetate.  |  Tao, N., et al. 2019. Org Lett. 21: 8607-8610. PMID: 31621337
  7. Advancement in Determination of Phthalate Metabolites by Gas Chromatography Eliminating Derivatization Step.  |  Tankiewicz, M., et al. 2019. Front Chem. 7: 928. PMID: 32010672
  8. Phthalate metabolites in harbor porpoises (Phocoena phocoena) from Norwegian coastal waters.  |  Rian, MB., et al. 2020. Environ Int. 137: 105525. PMID: 32028175
  9. Risk assessment for humans using physiologically based pharmacokinetic model of diethyl phthalate and its major metabolite, monoethyl phthalate.  |  Jeong, SH., et al. 2020. Arch Toxicol. 94: 2377-2400. PMID: 32303804
  10. Prenatal phthalate exposures and autism spectrum disorder symptoms in low-risk children.  |  Haggerty, DK., et al. 2021. Neurotoxicol Teratol. 83: 106947. PMID: 33412243
  11. Demographic Assessment of Mono(2-ethylhexyl) Phthalate (MEHP) and Monoethyl Phthalate (MEP) Concentrations in Common Bottlenose Dolphins (Tursiops truncatus) From Sarasota Bay, FL, USA.  |  Dziobak, MK., et al. 2021. Geohealth. 5: e2020GH000348. PMID: 34036207
  12. Does early life phthalate exposure mediate racial disparities in children's cognitive abilities?  |  Patti, MA., et al. 2022. Environ Epidemiol. 6: e205. PMID: 35434463
  13. Determinants of urinary phthalate biomarker concentrations in pre- and perimenopausal women with consideration of race.  |  Ryva, BA., et al. 2022. Environ Res. 214: 114056. PMID: 35952743

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Monoethyl Phthalate, 100 mg

sc-505736
100 mg
$350.00