Molecular structure of (−)-U-50488 hydrochloride, CAS Number: 67198-19-0
(−)-U-50488 hydrochloride (CAS 67198-19-0)
Alternate Names:
trans-(−)-3,4-Dichloro-N-methyl-N-[2-(1-pyrrolidinyl)cyclohexyl]benzeneacetamide hydrochloride
CAS Number:
67198-19-0
Purity:
≥98%
Molecular Weight:
405.79
Molecular Formula:
C19H26Cl2N2O•HCl
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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SDS & Certificate of Analysis
(−)-U-50488 hydrochloride is a compound that functions as a selective κ-opioid receptor agonist. It acts by binding to and activating the κ-opioid receptor, leading to a cascade of intracellular signaling events. This activation ultimately results in the modulation of neurotransmitter release, particularly of dopamine, and the inhibition of neuronal excitability. At the molecular level, (−)-U-50488 hydrochloride interacts with the κ-opioid receptor, leading to conformational changes and the initiation of downstream signaling pathways. (−)-U-50488 Hydrochloride′s mechanism of action involves the regulation of synaptic transmission and neuronal activity, which can have implications for studying the role of κ-opioid receptors in various physiological and pathological processes.
(−)-U-50488 hydrochloride (CAS 67198-19-0) References
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- Oxytocin Is a Positive Allosteric Modulator of κ-Opioid Receptors but Not Δ-Opioid Receptors in the G Protein Signaling Pathway. | Miyano, K., et al. 2021. Cells. 10: PMID: 34685631
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KOR.Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
(−)-U-50488 hydrochloride, 5 mg | sc-203714 | 5 mg | $155.00 | |||
(−)-U-50488 hydrochloride, 25 mg | sc-203714A | 25 mg | $510.00 |