MICAL1 Antibody (3D12): sc-293357
- MICAL1 Antibody (3D12) is a mouse monoclonal IgG2a κ provided at 100 µg/ml
- raised against amino acids 971-1067 of MICAL1 of human origin
- recommended for detection of MICAL1 of human origin by WB, IP and ELISA
- At present, we have not yet completed the identification of the preferred secondary detection reagent(s) for MICAL1 Antibody (3D12). This work is in progress.
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MICAL1 Antibody (3D12) is a mouse monoclonal IgG2a antibody that detects MICAL1 in human samples through applications such as western blotting (WB), immunoprecipitation (IP), and enzyme-linked immunosorbent assay (ELISA). MICAL1, or microtubule associated monooxygenase, calponin and LIM domain containing 1, is a 1,067 amino acid protein that plays a crucial role in cytoskeletal regulation, localizing to both the cytoplasm and the cytoskeleton. MICAL1 contains one LIM zinc-binding domain and one calponin-homology domain, which are essential for interactions with other proteins. MICAL1 is expressed in various tissues, including the kidney, thymus, spleen, lung, and testis, and interacts with several key proteins such as the SH3 domain of Cas-L, Rab 1B, plexin-A3, and Vimentin. These interactions are vital for regulating cytoskeletal dynamics and may contribute to processes like axonal repulsion, which is important for neuronal development and function. MICAL1 exists in three isoforms due to alternative splicing, adding another layer of complexity to regulatory functions in cellular processes. Anti-MICAL1 antibody (3D12) is an invaluable tool for researchers studying the intricate roles of this protein in human biology.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
MICAL1 Antibody (3D12) | sc-293357 | 100 µg/ml | $322.00 |