Date published: 2025-12-5

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Methyl Dimethylbenzeneacetate (CAS 57625-74-8)

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Alternate Names:
Methyl 2-methyl-2-phenylpropanoate
CAS Number:
57625-74-8
Purity:
≥98%
Molecular Weight:
178.23
Molecular Formula:
C11H14O2
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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Methyl dimethylbenzeneacetate is a specialized chemical used primarily in organic synthesis and materials science research. Its molecular structure features a benzene ring substituted with acetate and methyl groups, which enhances its solubility and reactivity in organic solvents, making it an ideal candidate for use in synthesizing complex organic compounds. This chemical serves as a precursor in the synthesis of aromatic compounds, which are crucial for developing new polymers, resins, and other industrial materials. In the realm of synthetic chemistry, methyl dimethylbenzeneacetate is utilized to study Friedel-Crafts acylation reactions, where it acts as an acyl donor in the presence of Lewis acids to form ketones, which are key intermediates in the manufacture of fine chemicals and pharmaceuticals. Moreover, the reactivity of methyl dimethylbenzeneacetate allows researchers to explore novel pathways for creating functionalized aromatic compounds that can be used in the development of advanced materials with specific optical, electrical, or mechanical properties. These applications are critical for innovations in electronics, automotive, and aerospace industries. The compound is also employed in method development for catalytic processes that aim to increase efficiency and selectivity in industrial chemistry. Through these diverse applications, methyl dimethylbenzeneacetate contributes significantly to the enhancement of material properties and the exploration of new synthetic routes in chemistry, providing valuable insights into the design and fabrication of next-generation materials.


Methyl Dimethylbenzeneacetate (CAS 57625-74-8) References

  1. Synthesis, spectral characterization and biological evaluation of a novel series of 6-arylsubstituted-3-[2-(4-substitutedphenyl)propan-2-yl]-7H-[1,2,4]triazolo[3,4-b][1,3,4]thiadiazines.  |  Puthiyapurayil, P., et al. 2012. Eur J Med Chem. 57: 407-16. PMID: 22819504
  2. Metalation of cumene with n-pentylsodium in the presence of N, N, N', N'-tetramethylethylenediamine. Preparation of. alpha.-cumylsodium.  |  Crimmins, Timothy F. and Coretta M. Chan. 1976. The Journal of Organic Chemistry. 41.10: 1870-1872.
  3. Photolyses of [2-Substituted 2-(alkoxycarbonyl) propyl] cobaloximes.  |  Tada, Masaru, et al. 1982. Bulletin of the Chemical Society of Japan. 55.12: 3939-3940.
  4. Spectroscopy and Photochemistry of Phenylacetic Acid Esters and Related Substrates. The Stereoelectronic Dependence of the Aryl/Carboxyl Bichromophore Interaction.  |  Kasper, Annette M., et al. 1994. The Journal of Organic Chemistry. 59.10: 2792-2798.
  5. Synthesis and biological activities of a novel series of 3, 6‐disubstituted‐1, 2, 4‐triazolo‐[3, 4‐b]‐1, 3, 4‐thiadiazoles containing gem‐dimethylbenzyl moiety.  |  Puthiyapurayil, Pushpan, et al. 2011. Journal of Heterocyclic Chemistry. 48.5: 998-1005.
  6. A New and Competitive Synthetic Approach for an Antihistamine Agent, Bilastine.  |  Kommera, Rajashekar, et al. 2018. Letters in Organic Chemistry. 15.10: 815-821.
  7. An Adaptive Auto‐Synthesizer Using Online PAT Feedback to Flexibly Perform a Multistep Reaction.  |  Liu, Junliang, et al. 2022. Chemistry‐Methods. 2.8: e202200009.
  8. An Update on Phosphine‐Imidazolin‐2‐Imine Iridium (I) Catalysts for Hydrogen Isotope Exchange.' Advanced Synthesis & Catalysis  |  Becker, Daniel, et al. 2023. Advanced Synthesis & Catalysis. 365.3: 367-372.

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Methyl Dimethylbenzeneacetate, 1 g

sc-338018
1 g
$560.00