Molecular structure of Methyl chlorooxoacetate, CAS Number: 5781-53-3
Methyl chlorooxoacetate (CAS 5781-53-3)
Alternate Names:
Methyl chloroglyoxylate
CAS Number:
5781-53-3
Molecular Weight:
122.51
Molecular Formula:
C3H3ClO3
Supplemental Information:
This is classified as a Dangerous Good for transport and may be subject to additional shipping charges.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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Methyl chlorooxoacetate is a synthetic reagent. As a derivative of chloroform, it serves as a valuable reagent for synthesizing a wide range of organic compounds, making it essential in numerous biochemical and physiological studies. Its uses extend to the synthesis of various products, including dyes, fragrances, and pesticides, while also playing a role in the production of polymers and plastics.
Methyl chlorooxoacetate (CAS 5781-53-3) References
- An effective procedure for the acylation of azaindoles at C-3. | Zhang, Z., et al. 2002. J Org Chem. 67: 6226-7. PMID: 12182666
- An efficient and scalable synthesis of substituted phenanthrenequinones by intramolecular Friedel-Crafts reaction of imidazolides. | Yoshikawa, N., et al. 2007. Org Lett. 9: 4103-6. PMID: 17880225
- Synthesis of biologically active N-methyl derivatives of amidines and cyclized five-membered products of amidines with oxalyl chloride. | Sondhi, SM., et al. 2008. Eur J Med Chem. 43: 2824-30. PMID: 18022734
- Synthesis of 2'-C-beta-methyl-2'-deoxyguanosine. | Li, NS., et al. 2009. J Org Chem. 74: 2227-30. PMID: 19173609
- 2,2,2-Trifluoroethyl Chlorooxoacetate--Universal Reagent for One-Pot Parallel Synthesis of N(1)-Aryl-N(2)-alkyl-Substituted Oxamides. | Bogolubsky, AV., et al. 2015. ACS Comb Sci. 17: 615-22. PMID: 26325360
- Introducing an α-Keto Ester Functional Group through Pt-Catalyzed Direct C-H Acylation with Ethyl Chlorooxoacetate. | Javed, E., et al. 2020. ACS Omega. 5: 8393-8402. PMID: 32309750
- A2B- and A3-Type Boron(III)Subchlorins Derived from meso-Diethoxycarbonyltripyrrane: Synthesis and Photophysical Exploration. | Soman, R., et al. 2021. J Org Chem. 86: 10280-10287. PMID: 34264670
- Efficient access to aliphatic esters by photocatalyzed alkoxycarbonylation of alkenes with alkyloxalyl chlorides. | Chen, JQ., et al. 2021. Nat Commun. 12: 5328. PMID: 34493725
- Free radical-mediated carboxylation by radical reaction of alkyl iodides with methyl oxalyl chloride | Sunggak Kim ∗, Sang Yong Jon. 1998,. Tetrahedron Letters. 39: 7317-7320.
- A novel method for the efficient synthesis of methyl 2-oxo-2-arylacetates and its application to the preparation of fungicidal methyl (E)-O-methyloximino-2-arylacetates and their (Z)-stereoisomers | Renzo Rossi ∗ a 2, Adriano Carpita ∗ a, Piergiorgio Pazzi a, Luisa Mannina b, Daniela Valensin c. 1999. Tetrahedron. 55: 11343-11364.
- Experimental and theoretical study of the homogeneous, unimolecular gas-phase elimination kinetics of methyl oxalyl chloride | Tania Cordova, Alexandra Rotinov, Gabriel Chuchani. 2004. Journal of Physical Organic Chemistry. 17: 148-151.
- Ring opening of 2-acylaziridines by acid chlorides | Yongeun Kim a, Hyun-Joon Ha a b, Hoseop Yun c, Baeck Kyoung Lee d, Won Koo Lee d. 2006. Tetrahedron. 62: 8844-8849.
- An efficient one-pot synthesis of 3-glyoxylic acids of electron-deficient substituted azaindoles by ionic liquid imidazolium chloroaluminate-promoted Friedel–Crafts acylation | Kap-Sun Yeung, Zhilei Qiu, Michelle E. Farkas, Qiufen Xue, Alicia Regueiro-Ren, Zhong Yang, John A. Bender, Andrew C. Good, John F. Kadow. 2008. Tetrahedron Letters. 49: 6250-6253.
- In situ DRIFTS study of CO coupling to dimethyl oxalate over structured Al-fiber@ns-AlOOH@Pd catalyst | Chunzheng Wang, Pengjing Chen, Yakun Li, Guofeng Zhao, Ye Liu, Yong Lu. 2016. Journal of Catalysis. 344: 173-183.
- Visible-light-induced alkoxycarbonylation/cyclization of 1,7-enynes: synthesis of dihydropyranones containing all-carbon quaternary centers | Jian-Qiang Chen,a Qi Chen,a Baofu Chen*a and Jie Wu *abc . 2023. Org. Chem. Front. 10: 2018-2023.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Methyl chlorooxoacetate, 5 g | sc-250367 | 5 g | $31.00 | |||
Methyl chlorooxoacetate, 25 g | sc-250367A | 25 g | $165.00 |