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Methyl Acetylsalicylate (CAS 580-02-9)

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Alternate Names:
Acetylsalicylic Acid Methyl Ester; Methyl 2-Acetoxybenzoate
Application:
Methyl Acetylsalicylate is an ester for for proteomics research
CAS Number:
580-02-9
Purity:
≥98%
Molecular Weight:
194.18
Molecular Formula:
C10H10O4
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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Methyl Acetylsalicylate functions as an acetylating agent in organic synthesis. It acts by transferring an acetyl group to hydroxyl groups, such as those found in phenols and alcohols, to form esters. This process involves the nucleophilic attack of the hydroxyl group on the acetyl group, resulting in the formation of an ester bond and the release of acetic acid. In this way, Methyl Acetylsalicylate plays a role in the modification of organic molecules, allowing for the synthesis of various ester derivatives. Its mechanism of action involves the acetylation of specific functional groups, leading to the formation of new chemical compounds with altered properties. Methyl Acetylsalicylate′s function in experimental applications involves its role as an acetylating agent, facilitating the modification of organic molecules through ester formation.


Methyl Acetylsalicylate (CAS 580-02-9) References

  1. Methyl salicylate: a reactive chemical warfare agent surrogate to detect reaction with hypochlorite.  |  Salter, WB., et al. 2011. ACS Appl Mater Interfaces. 3: 4262-7. PMID: 21981047
  2. Selective Nickel-Catalyzed Hydrodeacetoxylation of Aryl Acetates.  |  De Smet, G., et al. 2022. Angew Chem Int Ed Engl. 61: e202201751. PMID: 35373882
  3. Isolation of salicylsalicylic acid, acetylsalicylsalicylic acid, and acetylsalicylic anhydride from aspirin tablets by extraction and high-pressure liquid chromatography.  |  Reepmeyer, JC. and Kirchhoefer, RD. 1979. J Pharm Sci. 68: 1167-9. PMID: 501542
  4. The effect of methyl acetylsalicylate on renal tubular ionic reabsorption.  |  Ramsay, AG., et al. 1969. Proc Soc Exp Biol Med. 132: 307-13. PMID: 5344852
  5. Increase in the activity of Rhizopus delemar lipase on water-soluble esters by its binding with phosphatidylcholine.  |  Shimada, Y., et al. 1983. J Biochem. 93: 1655-60. PMID: 6885742
  6. Application of high performance liquid chromatography and field desorption mass spectroscopy to separative analysis of bitter secoiridoid glucosides of Swertiae Herba  |  SAKAMOTO, I., MORIMOTO, K., TANAKA, O., & INOUYE, H. 1983. Chemical and Pharmaceutical Bulletin. 31(1): 25-30.
  7. Cyclodextrin complexation of NSAIDSs: physicochemical characteristics  |  Loftsson, T., Ólafsdóttir, B. J., Friðriksdóttir, H., & Jónsdóttir, S. 1993. European Journal of Pharmaceutical Sciences. 1(2): 95-101.

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Methyl Acetylsalicylate, 25 g

sc-396991
25 g
$57.00