Date published: 2026-1-21

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methyl 6-aminohexanoate hydrochloride (CAS 1926-80-3)

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Application:
methyl 6-aminohexanoate hydrochloride is a synthesis reagent for straight chain hydroxamates
CAS Number:
1926-80-3
Molecular Weight:
181.66
Molecular Formula:
C7H16ClNO2
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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Methyl 6-aminohexanoate hydrochloride is a chemical compound primarily known for its role as an intermediate in the synthesis of peptides and various organic molecules. Structurally, it consists of a methyl ester linked to a 6-aminohexanoic acid, with a hydrochloride salt to improve its solubility and reactivity. This compound is particularly valued in research environments for its utility in facilitating the formation of amide bonds, a fundamental step in peptide coupling reactions. The presence of the amino group allows for selective functionalization, making it an indispensable tool in the construction of complex molecular architectures. Its application is in the field of organic chemistry, where it serves as a building block for the synthesis of a wide array of substances, ranging from small molecules to large biomolecules. The ability to easily manipulate its functional groups underpins its importance in studies focused on understanding molecular interactions and designing novel compounds with specific properties.


methyl 6-aminohexanoate hydrochloride (CAS 1926-80-3) References

  1. Conjugates of doxorubicin with graft HPMA copolymers for passive tumor targeting.  |  Etrych, T., et al. 2008. J Control Release. 132: 184-92. PMID: 18534705
  2. Novel amide derivatives as inhibitors of histone deacetylase: design, synthesis and SAR.  |  Andrianov, V., et al. 2009. Eur J Med Chem. 44: 1067-85. PMID: 18672316
  3. The investigation of structural and thermosensitive properties of new phosphazene derivatives bearing glycol and amino acid.  |  Uslu, A. and Güvenaltın, S. 2010. Dalton Trans. 39: 10685-91. PMID: 20938539
  4. Synthesis of 11C-labeled Kendine 91, a histone deacetylase inhibitor.  |  Aginagalde, M., et al. 2012. Appl Radiat Isot. 70: 2552-7. PMID: 22871301
  5. Direct observation of internalization and ROS generation of amyloid β-peptide in neuronal cells at subcellular resolution.  |  Jiao, Y., et al. 2012. Chembiochem. 13: 2335-8. PMID: 23060092
  6. Polymer carriers for anticancer drugs targeted to EGF receptor.  |  Studenovsky, M., et al. 2012. Macromol Biosci. 12: 1714-20. PMID: 23077133
  7. Synthesis and biological evaluation of biotin conjugates of (±)-(4bS,8aR,10aS)-10a-ethynyl-4b,8,8-trimethyl-3,7-dioxo-3,4b,7,8,8a,9,10,10a-octahydro-phenanthrene-2,6-dicarbonitrile, an activator of the Keap1/Nrf2/ARE pathway, for the isolation of its protein targets.  |  Saito, A., et al. 2013. Bioorg Med Chem Lett. 23: 5540-3. PMID: 24018193
  8. Phenylpyrrole-based HDAC inhibitors: synthesis, molecular modeling and biological studies.  |  Brindisi, M., et al. 2016. Future Med Chem. 8: 1573-87. PMID: 27556815
  9. Effect of dehydrocholic acid conjugated with a hydrocarbon on a lipid bilayer composed of 1,2-dioleoyl-sn-glycero-3-phosphocholine.  |  Hayashi, K., et al. 2019. Colloids Surf B Biointerfaces. 181: 58-65. PMID: 31121382
  10. Discovery of a novel rhein-SAHA hybrid as a multi-targeted anti-glioblastoma drug.  |  Chen, J., et al. 2020. Invest New Drugs. 38: 755-764. PMID: 31414267
  11. Synthesis of Peptoid-Based Class I-Selective Histone Deacetylase Inhibitors with Chemosensitizing Properties.  |  Krieger, V., et al. 2019. J Med Chem. 62: 11260-11279. PMID: 31762274
  12. Discovery of thiosemicarbazone-containing compounds with potent anti-proliferation activity against drug-resistant K562/A02 cells.  |  Gu, X., et al. 2020. Bioorg Med Chem Lett. 30: 127638. PMID: 33132117
  13. Syntheses of biotinylated and dethiobiotinylated insulins.  |  Hofmann, K., et al. 1984. Biochemistry. 23: 2547-53. PMID: 6380570
  14. Avidin binding of carboxyl-substituted biotin and analogues.  |  Hofmann, K., et al. 1982. Biochemistry. 21: 978-84. PMID: 7041971
  15. Texas Res-X and rhodamine Red-X, new derivatives of sulforhodamine 101 and lissamine rhodamine B with improved labeling and fluorescence properties.  |  Lefevre, C., et al. 1996. Bioconjug Chem. 7: 482-9. PMID: 8853462

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

methyl 6-aminohexanoate hydrochloride, 10 g

sc-279412
10 g
$234.00