Date published: 2025-9-5

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Metam sodium (CAS 137-42-8)

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Alternate Names:
Carbathione
CAS Number:
137-42-8
Molecular Weight:
129.18
Molecular Formula:
C2H4NNaS2
Supplemental Information:
This is classified as a Dangerous Good for transport and may be subject to additional shipping charges.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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Metam sodium, is widely recognized for its ability to decompose into methyl isothiocyanate (MITC) when in contact with soil and water, a transformation that is the subject of much scientific interest. It is often used in studies aimed at determining its stability, degradation products, and reaction kinetics. A point of focus in environmental chemistry, where its interaction with other elements in the ecosystem is examined. This includes research into its mobility in soils, its transformation products, and its distribution in the environment. Metam sodium is important in analytical chemistry where it is used as a standard or reagent in the development of analytical methods. Its predictable behavior under certain conditions makes it suitable for use in calibrating instruments and validating experimental procedures.


Metam sodium (CAS 137-42-8) References

  1. Influence of metam sodium on the dissipation and residual biological activity of the herbicides EPTC and pebulate in surface soil under black plastic mulch.  |  Stiles, CL., et al. 2000. J Agric Food Chem. 48: 4681-6. PMID: 11052719
  2. Transformation of chloropicrin and 1,3-dichloropropene by metam sodium in a combined application of fumigants.  |  Zheng, W., et al. 2004. J Agric Food Chem. 52: 3002-9. PMID: 15137846
  3. Incompatibility of metam sodium with halogenated fumigants.  |  Guo, M., et al. 2005. Pest Manag Sci. 61: 467-76. PMID: 15816019
  4. Accelerated degradation of metam-sodium in soil and consequences for root-disease management.  |  Triky-Dotan, S., et al. 2009. Phytopathology. 99: 362-8. PMID: 19271977
  5. Microbial aspects of accelerated degradation of metam sodium in soil.  |  Triky-Dotan, S., et al. 2010. Phytopathology. 100: 367-75. PMID: 20205540
  6. Metam sodium intoxication: the specific role of degradation products--methyl isothiocyanate and carbon disulphide--as a function of exposure.  |  Bretaudeau Deguigne, M., et al. 2011. Clin Toxicol (Phila). 49: 416-22. PMID: 21740140
  7. Determination of methyl isocyanate in outdoor residential air near metam-sodium soil fumigations.  |  Woodrow, JE., et al. 2014. J Agric Food Chem. 62: 8921-7. PMID: 25144617
  8. Comparison of Ethanedinitrile (C2N2) and Metam Sodium for Control of Bursaphelenchus xylophilus (Nematoda: Aphelenchidae) and Monochamus alternatus (Coleoptera: Cerambycidae) in Naturally Infested Logs at Low Temperatures.  |  Park, CG., et al. 2014. J Econ Entomol. 107: 2055-60. PMID: 26470069
  9. Effects of fumigation with metam-sodium on soil microbial biomass, respiration, nitrogen transformation, bacterial community diversity and genes encoding key enzymes involved in nitrogen cycling.  |  Li, J., et al. 2017. Sci Total Environ. 598: 1027-1036. PMID: 28476076
  10. Ecotoxicity of 1,3-dichloropropene, metam sodium, and dazomet on the earthworm Eisenia fetida with modified artificial soil test and natural soil test.  |  Mao, L., et al. 2017. Environ Sci Pollut Res Int. 24: 18692-18698. PMID: 28669094
  11. Effects of Sublabeled Rates of Dazomet and Metam-Sodium Applied Under Low-Permeability Films on Calonectria Microsclerotia Survival.  |  Aiello, D., et al. 2018. Plant Dis. 102: 782-789. PMID: 30673406
  12. Comparison of Drip and Sprinkler Irrigation Systems for Applying Metam Sodium and Managing Stem Rot on Potato.  |  Browne, GT., et al. 2002. Plant Dis. 86: 1211-1218. PMID: 30818469
  13. Prenatal exposure to the pesticide metam sodium induces sensorimotor and neurobehavioral abnormalities in mice offspring.  |  Kaikai, NE., et al. 2020. Environ Toxicol Pharmacol. 74: 103309. PMID: 31835201
  14. Metam sodium exposure during pregnancy and lactation in mice caused behavioral abnormalities and oxidative stress in offspring.  |  Kaikai, NE., et al. 2021. Environ Toxicol Pharmacol. 85: 103630. PMID: 33711515
  15. Chronic exposure to metam sodium-based pesticide in mice during adulthood elevated anxiety and depression-like behaviors: Involvement of serotoninergic depletion and gut microbiota dysbiosis.  |  Kaikai, NE., et al. 2023. Environ Toxicol Pharmacol. 98: 104066. PMID: 36640922
  16. Mechanistic investigation of the differential synergistic neurotoxicity between pesticide metam sodium and copper or zinc.  |  Shen, C., et al. 2023. Chemosphere. 328: 138430. PMID: 36963585

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Metam sodium, 1 g

sc-257700
1 g
$215.00