Magnesium ionophore IV (CAS 135734-39-3)

Magnesium ionophore IV is a specialized chemical tool used primarily in the field of cellular biology to study intracellular magnesium (Mg2+) concentrations and transport mechanisms. By facilitating the selective passage of Mg2+ across lipid bilayer membranes, this ionophore is integral in creating controlled intracellular environments for research. It allows for the modulation of Mg2+ levels in cells, thereby enabling the investigation of how these ions influence various cellular processes such as enzyme activity, DNA synthesis, and ion channel function. Additionally, magnesium ionophore IV is useful in the study of signal transduction pathways where Mg2+ acts as a cofactor, affecting the activity of kinases and phosphatases. In neurobiology, it helps in the exploration of the role of Mg2+ in neuronal excitability and neurotransmitter release. The ionophore′s ability to perturb intracellular magnesium concentrations also makes it useful in the study of cardiovascular function, given the importance of Mg2+ in cardiac ion channel regulation and muscle contraction.