Date published: 2026-1-10

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LY 395756 (CAS 852679-66-4)

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Alternate Names:
(1S,2S,4R,5R,6S)-rel-2-Amino-4-methylbicyclo[3.1.0]hexane-2,6-dicarboxylic acid
Application:
(±)LY 395756 is a selective, metabotropic glutamate ligand for the mGluR-2 and mGluR-3 receptors
CAS Number:
852679-66-4
Molecular Weight:
199.20
Molecular Formula:
C9H13NO4
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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LY 395756 is a selective, metabotropic glutamate ligand for the mGlu2 and mGlu3 receptors. For the mGlu2 receptor, this compund acts as an agonist.This compound acts as an antagonist at the mGlu3 receptor. Additionally, this compund is an analog of LY 354740 (sc-204064).


LY 395756 (CAS 852679-66-4) References

  1. Methyl substitution of 2-aminobicyclo[3.1.0]hexane 2,6-dicarboxylate (LY354740) determines functional activity at metabotropic glutamate receptors: identification of a subtype selective mGlu2 receptor agonist.  |  Dominguez, C., et al. 2005. J Med Chem. 48: 3605-12. PMID: 15887967

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

(±)LY 395756, 10 mg

sc-359013
10 mg
$176.00

(±)LY 395756, 50 mg

sc-359013A
50 mg
$982.00