Molecular structure of LY 266097 hydrochloride, CAS Number: 172895-39-5
LY 266097 hydrochloride (CAS 172895-39-5)
Alternate Names:
1-[(2-Chloro-3,4-dimethoxyphenyl)methyl]-2,3,4,9-tetrahydro-6-methyl-1H-pyrido[3,4-b]indole hydrochloride
Application:
LY 266097 hydrochloride is A selective SR-2B receptor antagonist
CAS Number:
172895-39-5
Molecular Weight:
407.33
Molecular Formula:
C21H23ClN2O2•HCl
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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SDS & Certificate of Analysis
LY 266097 hydrochloride has been shown to be an extremely selective 5-HT2B receptor antagonist.
LY 266097 hydrochloride (CAS 172895-39-5) References
- The central serotonin 2B receptor: a new pharmacological target to modulate the mesoaccumbens dopaminergic pathway activity. | Auclair, AL., et al. 2010. J Neurochem. 114: 1323-32. PMID: 20534001
- Stimulating DDX3 expression by serotonin 5-HT receptor 7 through phosphorylation of p53 via the AC-PKA-ERK signaling pathway. | Kang, LJ., et al. 2019. J Cell Biochem. 120: 18193-18208. PMID: 31172579
- Potent, selective tetrahydro-beta-carboline antagonists of the serotonin 2B (5HT2B) contractile receptor in the rat stomach fundus. | Audia, JE., et al. 1996. J Med Chem. 39: 2773-80. PMID: 8709108
- GPCR-IFP: A Web Server for Analyzing G-Protein Coupled Receptor-Ligand Fingerprint Interaction from Experimental Structures[J]. | Xu M, li Y, Dong J. 2022: bioRxiv,. 2022.03. 16.: 484667.
Inhibitor of:
SR, and SR-2B.Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
LY 266097 hydrochloride, 10 mg | sc-361240 | 10 mg | $213.00 | |||
LY 266097 hydrochloride, 50 mg | sc-361240A | 50 mg | $898.00 |