Levofloxacin-d8 (CAS 1217716-71-6)

Levofloxacin-d8 is a chemically modified version of levofloxacin, distinguished by the substitution of eight hydrogen atoms with deuterium, a stable and non-radioactive isotope of hydrogen. This alteration significantly contributes to the utility of Levofloxacin-d8 in research environments, particularly in the fields of analytical chemistry and environmental science. The incorporation of deuterium not only enhances the molecular stability of levofloxacin, making it less susceptible to degradation over time, but also increases its molecular weight slightly, which facilitates its identification and quantification in mass spectrometric analysis. Researchers utilize Levofloxacin-d8 primarily as an internal standard in quantitative mass spectrometry studies to ensure more accurate, precise, and reproducible measurements of the parent molecule in complex biological and environmental samples. This is critical in experiments where exact quantification is necessary to understand the dynamics of levofloxacin under various conditions. Moreover, Levofloxacin-d8 plays a pivotal role in metabolic studies, aiding in the tracing and elucidation of metabolic pathways of levofloxacin through its distinguishable isotopic pattern. These capabilities make it an essential tool in studies aiming to map out the distribution, persistence, and transformation of levofloxacin in different environmental compartments, contributing to a broader understanding of its interactions and impacts.