Date published: 2025-10-1

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Leukotriene C4 methyl ester (CAS 73958-10-8)

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Application:
Leukotriene C4 methyl ester is a more lipid-soluble form of LTC4
CAS Number:
73958-10-8
Molecular Weight:
639.80
Molecular Formula:
C31H49N3O9S
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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Leukotriene C4 methyl ester (LTC4 methyl ester) is a more lipid soluble form of LTC4, which is one of the main constituents of slow-reacting substance of anaphylaxis (SRS-A) and exhibits potent smooth muscle contracting activity.


Leukotriene C4 methyl ester (CAS 73958-10-8) References

  1. Prostaglandins and leukotrienes: advances in eicosanoid biology.  |  Funk, CD. 2001. Science. 294: 1871-5. PMID: 11729303
  2. Glutathione S-transferase-dependent conjugation of leukotriene A4-methyl ester to leukotriene C4-methyl ester in mammalian skin.  |  Agarwal, R., et al. 1992. Biochem Pharmacol. 44: 2047-53. PMID: 1449522
  3. Facile preparation of leukotrienes C(4), D(4) and E(4) containing carbon-13 and nitrogen-15 for quantification of cysteinyl leukotrienes by mass spectrometry.  |  Ghomashchi, F., et al. 2007. J Labelled Comp Radiopharm. 50: 729-733. PMID: 18516250
  4. Leukotriene C4 synthesis catalyzed by Dirofilaria immitis glutathione S-transferase.  |  Weller, PF., et al. 1989. Am J Trop Med Hyg. 40: 171-5. PMID: 2493201
  5. Transcellular metabolism of neutrophil-derived leukotriene A4 by human platelets. A potential cellular source of leukotriene C4.  |  Maclouf, JA. and Murphy, RC. 1988. J Biol Chem. 263: 174-81. PMID: 2826437
  6. Leukotrienes as mediators of ischemia and shock.  |  Lefer, AM. 1986. Biochem Pharmacol. 35: 123-7. PMID: 3002383
  7. Racemic LTA4 methyl ester bioconversion into LTC4 methyl ester by various glutathione S-transferases.  |  Maury, G., et al. 1987. Biochem Int. 15: 1127-35. PMID: 3125835
  8. Prediction and associations of preterm birth and its subtypes with eicosanoid enzymatic pathways and inflammatory markers.  |  Aung, MT., et al. 2019. Sci Rep. 9: 17049. PMID: 31745121
  9. Leukotrienes: mediators of immediate hypersensitivity reactions and inflammation.  |  Samuelsson, B. 1983. Science. 220: 568-75. PMID: 6301011
  10. Formation and actions of leukotrienes.  |  Piper, PJ. 1984. Physiol Rev. 64: 744-61. PMID: 6324254

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Leukotriene C4 methyl ester, 25 µg

sc-205370
25 µg
$154.00

Leukotriene C4 methyl ester, 50 µg

sc-205370A
50 µg
$294.00