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Lead(IV) acetate (CAS 546-67-8)

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Datasheets
Alternate Names:
Tetrakis(acetyloxy)plumbane
Application:
Lead(IV) acetate is induces the addition of difluorodiiodomethane to alkynes and alkenes
CAS Number:
546-67-8
Purity:
≥90%
Molecular Weight:
443.38
Molecular Formula:
C8H12O8Pb
Supplemental Information:
This is classified as a Dangerous Good for transport and may be subject to additional shipping charges.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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Lead(IV) acetate is a chemical compound utilized primarily in organic synthesis and materials science research. It functions as an oxidizing agent in a variety of organic reactions, including the oxidation of alcohols to aldehydes and ketones. In materials science, Lead(IV) acetate is investigated for its potential use in the preparation of lead-based oxides, which are of interest for their electronic and catalytic properties. The compound also serves as a starting material for the synthesis of other lead compounds that are studied for their unique chemical reactivity and role in the development of lead-containing materials. Additionally, due to its oxidizing power, Lead(IV) acetate is used to study the mechanisms of oxidative stress in inorganic systems and the stabilization of high oxidation states in lead compounds.


Lead(IV) acetate (CAS 546-67-8) References

  1. Reactions of chloride salts of 7-amino-9-ethylguanine and 1-amino-3-methylbenzimidazoles with lead(IV) acetate: formation of 8-aza-9-ethylguanine and 1-methyl-1H-benzotriazoles.  |  Kaiya, T., et al. 1999. Bioorg Med Chem Lett. 9: 961-4. PMID: 10230620
  2. Production of 16beta-(acetoxy)acetoxy derivatives by reaction of 17-keto steroid enol acetates with lead (IV) acetate.  |  Numazawa, M., et al. 2001. Steroids. 66: 743-8. PMID: 11522336
  3. Potentiometric determination of famotidine in pharmaceutical formulations.  |  Ayad, MM., et al. 2002. J Pharm Biomed Anal. 29: 247-54. PMID: 12062684
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  5. Synthesis of fullerene-fused lactones and fullerenyl esters: radical reaction of [60]fullerene with carboxylic acids promoted by manganese(III) acetate and lead(IV) acetate.  |  Li, FB., et al. 2009. J Org Chem. 74: 7743-9. PMID: 19761269
  6. First enantiospecific synthesis of marine sesquiterpene quinol akaol A.  |  Alvarez-Manzaneda, E., et al. 2012. Chem Commun (Camb). 48: 606-8. PMID: 22073392
  7. Diastereoselective synthesis of 5-hydroxy-8-methoxy-1-oxaspiro[5,5]undeca-7,10-diene-9-one.  |  Plourde, GL. and Scully, TW. 2013. Molecules. 18: 1174-80. PMID: 23344206
  8. Formation of Fused Aromatic Architectures via an Oxidative Dearomatization - Radical Cyclization Rearomatization Approach.  |  Vitaku, E. and Njardarson, JT. 2015. Tetrahedron Lett. 56: 3550-3552. PMID: 26236054
  9. Neuroglobin in Breast Cancer Cells: Effect of Hypoxia and Oxidative Stress on Protein Level, Localization, and Anti-Apoptotic Function.  |  Fiocchetti, M., et al. 2016. PLoS One. 11: e0154959. PMID: 27149623
  10. Effect of Lead(IV) Acetate on Procoagulant Activity in Human Red Blood Cells.  |  Kim, KY., et al. 2009. Toxicol Res. 25: 175-180. PMID: 32038835
  11. Deconjugative α-Alkylation of Cyclohexenecarboxaldehydes: An Access to Diverse Terpenoids.  |  Chahboun, R., et al. 2021. J Org Chem. 86: 8742-8754. PMID: 34128666
  12. [Oxidation of N-acetylserine and -threonine derivatives with lead (IV) acetate].  |  Oettmeier, W. 1970. Chem Ber. 103: 2314-6. PMID: 5433916
  13. Between basic and applied research: Ciba's involvement in steroids in the 1950s and 1960s.  |  Heusler, K. and Kalvoda, J. 1996. Steroids. 61: 492-503. PMID: 8870170

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Lead(IV) acetate, 25 g

sc-211729
25 g
$35.00

Lead(IV) acetate, 100 g

sc-211729A
100 g
$107.00