Date published: 2026-4-27

1-800-457-3801

SCBT Portrait Logo
Seach Input

Larixol (CAS 1438-66-0)

0.0(0)
Write a reviewAsk a question

Alternate Names:
(αS,1S,4S,4aS,8aR)-α-Ethenyldecahydro-4-hydroxy-α,5,5,8a-tetramethyl-2-methylene-1-naphthalenepropanol
CAS Number:
1438-66-0
Molecular Weight:
306.48
Molecular Formula:
C20H34O2
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

QUICK LINKS

Larixol is a naturally occurring organic compound that has garnered interest in various fields of scientific research. In studies of plant biology and phytochemistry, Larixol is investigated for its role in the defense mechanisms of larch trees against environmental stressors. It also serves as a chemical marker in dendrochronology to understand the growth patterns and age of trees. Additionally, researchers are interested in the synthesis of Larixol derivatives, aiming to explore their potential applications in materials science, such as in the creation of novel organic compounds with specific properties. In the realm of organic chemistry, the structure of Larixol is examined to understand the stereochemical outcomes of reactions involving terpenoids. Its role in ecological interactions, such as plant-insect relationships, is another area of study where Larixol′s biological activity is of significant interest.


Larixol (CAS 1438-66-0) References

  1. Mass spectrometric methodology for the analysis of highly oxidized diterpenoid acids in Old Master paintings.  |  Berg, KJ., et al. 2000. J Mass Spectrom. 35: 512-533. PMID: 10797648
  2. Gas chromatography/mass spectrometry characterization of historical varnishes of ancient Italian lutes and violin.  |  Echard, JP., et al. 2007. Anal Chim Acta. 584: 172-80. PMID: 17386601
  3. In vitro anti-inflammatory activity of larch (Larix decidua L.) sawdust.  |  Pferschy-Wenzig, EM., et al. 2008. J Agric Food Chem. 56: 11688-93. PMID: 19049343
  4. Characterization and Identification of Natural Terpenic Resins employed in 'Madonna con Bambino e Angeli' by Antonello da Messina using Gas Chromatography-Mass Spectrometry.  |  Russo, MV. and Avino, P. 2012. Chem Cent J. 6: 59. PMID: 22721351
  5. Identification and Validation of Larixyl Acetate as a Potent TRPC6 Inhibitor.  |  Urban, N., et al. 2016. Mol Pharmacol. 89: 197-213. PMID: 26500253
  6. Pharmacological inhibition of focal segmental glomerulosclerosis-related, gain of function mutants of TRPC6 channels by semi-synthetic derivatives of larixol.  |  Urban, N., et al. 2017. Br J Pharmacol. 174: 4099-4122. PMID: 28800680
  7. Reducing copper use in the environment: the use of larixol and larixyl acetate to treat downy mildew caused by Plasmopara viticola in viticulture.  |  Thuerig, B., et al. 2018. Pest Manag Sci. 74: 477-488. PMID: 28905481
  8. Contact allergy due to colophony (III). Sensitizing potency of resin acids and some related products.  |  Hausen, BM., et al. 1989. Contact Dermatitis. 20: 41-50. PMID: 2914435
  9. TRPC6 modulates adhesion of neutrophils to airway epithelial cells via NF-κB activation and ICAM-1 expression with ozone exposure.  |  Chen, QZ., et al. 2019. Exp Cell Res. 377: 56-66. PMID: 30779919
  10. Larch Wood Residues Valorization through Extraction and Utilization of High Value-Added Products.  |  Wagner, K., et al. 2020. Polymers (Basel). 12: PMID: 32041295
  11. Larixol inhibits fMLP-induced superoxide anion production and chemotaxis by targeting the βγ subunit of Gi-protein of fMLP receptor in human neutrophils.  |  Liao, HR., et al. 2022. Biochem Pharmacol. 201: 115091. PMID: 35569521
  12. Ageing behaviour and pyrolytic characterisation of diterpenic resins used as art materials: colophony and Venice turpentine  |  Dominique Scalarone, Massimo Lazzari, Oscar Chiantore. 2002. Journal of Analytical and Applied Pyrolysis. Volume 64, Issue 2: 345-361.
  13. Efficacy of extracts from eight economically important forestry species against grapevine downy mildew (Plasmopara viticola) and identification of active constituents  |  DA Mulholland, B Thuerig, MK Langat, L Tamm. 2017. Crop Protection. Volume 102: 104-109.

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Larixol, 50 mg

sc-488709
50 mg
$401.00