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Laminin is a pivotal glycoprotein integral to the structural scaffolding of basement membranes in almost every animal tissue. It plays a crucial role in many biological processes, including cell adhesion, differentiation, migration, and survival. Laminins are trimeric proteins that consist of alpha, beta, and gamma chains, which combine in various ways to form different isoforms, each adapted to specific functions and tissue types. Scientific research on laminin has extensively explored its role in the assembly of basement membranes and its interactions with other extracellular matrix components. These interactions are essential for tissue morphogenesis and the maintenance of tissue integrity. Laminin is also vital in signaling pathways that regulate cellular functions such as adhesion and movement. For instance, it can influence cell behavior through integrin receptors, dystroglycan complexes, and other cell surface receptors, which transduce signals affecting cellular dynamics and architecture. Moreover, studies have delved into the mechanistic details of how laminin contributes to the repair and regeneration of tissues. For example, in neural tissue, laminin is a key player in promoting neurite outgrowth, which is crucial for nerve regeneration. This property is harnessed in various experimental models to understand neurological recovery and regeneration mechanisms. The versatility of laminin makes it a focal point in developmental biology and tissue engineering research, where it is used to create biocompatible scaffolds that mimic natural tissue environments, facilitating studies on cell behavior and tissue formation under controlled conditions.
Ordering Information
Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Laminin | sc-29012 | 1 mg | $140.00 |