KNP-I Antibody (MM-7): sc-101055
- KNP-I Antibody (MM-7) is a mouse monoclonal IgG1 κ provided at 100 µg/ml
- raised against recombinant KNP-I of human origin
- recommended for detection of KNP-I of human origin, D10Jhu81e of mouse origin and the corresponding rat homolog by WB, IP, IF, IHC(P) and ELISA
- At present, we have not yet completed the identification of the preferred secondary detection reagent(s) for KNP-I Antibody (MM-7). This work is in progress.
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KNP-I Antibody (MM-7) is a mouse monoclonal IgG1 antibody that detects KNP-I in mouse, rat, and human samples through various applications including western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry with paraffin-embedded sections (IHCP), and enzyme-linked immunosorbent assay (ELISA). KNP-I, also known as ES1 protein homolog or protein GT335, is a ubiquitously expressed mitochondrial protein that plays a crucial role in cellular metabolism and energy production. KNP-I′s presence in mitochondria is vital, as KNP-I is involved in regulating metabolic pathways essential for maintaining cellular homeostasis. The gene encoding KNP-I, C21orf33, is located on human chromosome 21, near a region associated with several genetic disorders, including Down syndrome. KNP-I overexpression in individuals with Down syndrome may contribute to the disease′s pathology, highlighting KNP-I′s importance in both normal physiology and disease states. KNP-I exhibits highest expression levels in heart and muscle tissues, underscoring KNP-I′s significance in energy-demanding organs. KNP-I conservation across various species further emphasizes KNP-I′s fundamental biological role, making anti-KNP-I antibody (MM-7) an essential tool for researchers studying mitochondrial function and related diseases.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
KNP-I Antibody (MM-7) | sc-101055 | 100 µg/ml | $339.00 |