Date published: 2025-12-6

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Karaya gum (CAS 9000-36-6)

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Alternate Names:
Tragacanth Indian; Gum karaya from sterculia tree
Application:
Karaya gum is a thickener and emulsifier
CAS Number:
9000-36-6
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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Karaya gum, a natural polysaccharide derived from the exudate of Sterculia urens trees, has garnered significant attention in scientific research owing to its unique physicochemical properties and diverse applications. The mechanism of action of karaya gum is primarily attributed to its high molecular weight and branching structure, which imparts excellent thickening, stabilizing, and film-forming properties. In research, karaya gum has found utility in various fields, including food science, pharmaceuticals, and biotechnology. In food science, it serves as a natural thickener, stabilizer, and gelling agent in a wide range of food products, including dairy, bakery, and confectionery items. Its ability to form stable emulsions and enhance the texture and mouthfeel of food products makes it indispensable in food formulation research. Moreover, karaya gum has been explored for its potential as a mucoadhesive polymer in pharmaceutical formulations, particularly in oral mucosal drug delivery systems. Its bioadhesive properties enable prolonged drug residence at the site of application, enhancing drug absorption and bioavailability. Furthermore, karaya gum has been investigated as a biocompatible scaffold material in tissue engineering and regenerative medicine. Its biodegradability, non-toxicity, and ability to support cell attachment and growth make it a promising candidate for constructing tissue-engineered constructs and wound dressings. Overall, karaya gum′s multifunctional properties make it a valuable resource in various research endeavors aimed at developing novel materials and formulations for diverse applications.


Karaya gum (CAS 9000-36-6) References

  1. Compressed xanthan and karaya gum matrices: hydration, erosion and drug release mechanisms.  |  Munday, DL. and Cox, PJ. 2000. Int J Pharm. 203: 179-92. PMID: 10967440
  2. Formulation and in vitro evaluation of sustained release matrix tablets using cross-linked natural gum.  |  Jamil, QA., et al. 2017. Pak J Pharm Sci. 30: 355-362. PMID: 28649056
  3. Characteristics of karaya gum based films: Amelioration by inclusion of Schisandra chinensis oil and its oleogel in the film formulation.  |  Yousuf, B., et al. 2021. Food Chem. 345: 128859. PMID: 33333356
  4. Karaya/Gellan-Gum-Based Bilayer Films Containing 3,3'-Diindolylmethane-Loaded Nanocapsules: A Promising Alternative to Melanoma Topical Treatment.  |  Reolon, JB., et al. 2023. Pharmaceutics. 15: PMID: 37765203
  5. Quality by Design Approach for Optimization of Microbial and pH-Triggered Colon-Targeted Tablet Formulation Using Carboxymethyl Tamarind Gum.  |  Patel, J., et al. 2023. Assay Drug Dev Technol. 21: 297-308. PMID: 37831908
  6. New thickening agents based on tamarind seed gum and karaya gum polysaccharides[J].  |  Ibrahim N A, Abo-Shosha M H, Allam E A. 2010. Carbohydrate polymers., 81(2):: 402-408.
  7. Applications of gum karaya in drug delivery systems: a review on recent research.  |  Setia, Anupama, S. Goyal, and N. Goyal. 2010. Der Pharmacia Lettre. 2.5: 39-48.
  8. A novel green synthesis of silver nanoparticles using gum karaya: characterization, antimicrobial and catalytic activity studies[J].  |  Venkatesham M, Ayodhya D, Madhusudhan A. 2014,. Journal of Cluster Science,. 25: 409-422.
  9. Bioactivity and Characterization of Karaya Gum[J].  |  Samrot A V, Liana A, Emilin Renitta R. 2022. Journal of Pharmaceutical Negative Results. 744-751.
  10. Recent development in the medical and industrial applications of gum karaya: a review[J].  |  Prasad N, Thombare N, Sharma S C. 2023. Polymer Bulletin,., 80(4):: 3425-3447.

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Karaya gum, 500 g

sc-215205
500 g
$60.00