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Isobutyric acid (CAS 79-31-2)

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Alternate Names:
2-Methylpropionic acid
CAS Number:
79-31-2
Purity:
≥99%
Molecular Weight:
88.11
Molecular Formula:
C4H8O2
Supplemental Information:
This is classified as a Dangerous Good for transport and may be subject to additional shipping charges.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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Isobutyric acid (IBA) is a naturally occurring fatty acid that can be found in numerous plant and animal tissues. Its versatile applications span across the realms of the food and cosmetic industries. Within the realm of scientific exploration, Isobutyric acid serves various roles as a reagent, solvent, and a building block for synthesizing other compounds. In the realm of scientific investigation, Isobutyric acid finds a broad spectrum of uses. It frequently takes on the role of a reagent in organic synthesis, a solvent, and a valuable source for generating isobutyl esters. Furthermore, Isobutyric acid stands as a participant in the creation of diverse compounds like isobutyl alcohols and isobutyl halides. Notably, it assumes the role of a foundational model compound for delving into the structural and property intricacies of other organic substances. Isobutyric acid functions as an inhibitor for several enzymes pivotal in the carbohydrate and lipid metabolism. Demonstrably, it effectively curbs the activity of hexokinase, an enzyme central to glucose breakdown. The inhibition extends to fatty acid synthetase, a key player in fatty acid synthesis. Another noteworthy feat of Isobutyric acid is its capacity to hinder phospholipase A2, an enzyme pivotal in phospholipid breakdown.


Isobutyric acid (CAS 79-31-2) References

  1. Isobutyric acid from the Brindley's glands of Triatoma lecticularia.  |  Seigler, DS. and Lampman, RL. 2000. J Am Mosq Control Assoc. 16: 36-7. PMID: 10757489
  2. The utilization of the branched chain of isobutyric acid studied with C14.  |  GRAY, I., et al. 1950. Experientia. 6: 430-2. PMID: 14793542
  3. (18)O/(16)O isotope effect on miscibility of isobutyric acid with water.  |  Siporska, A., et al. 2007. J Phys Chem B. 111: 11632-4. PMID: 17877388
  4. A chemical test of the principle of critical point universality: the solubility of nickel (II) oxide in isobutyric acid + water near the consolute point.  |  Hu, B., et al. 2011. J Chem Phys. 134: 154505. PMID: 21513393
  5. Critical-point universality in adsorption: the effect of charcoal on a mixture of isobutyric acid and water near the consolute point.  |  Giesy, TJ., et al. 2011. Phys Rev E Stat Nonlin Soft Matter Phys. 83: 061201. PMID: 21797350
  6. Enhancing isobutyric acid production from engineered Acidithiobacillus ferrooxidans cells via media optimization.  |  Li, X., et al. 2016. Biotechnol Bioeng. 113: 790-6. PMID: 26370386
  7. Electrochemical techniques for evaluating short-chain fatty acid utilization by bioanodes.  |  Huang, W. and Kim, Y. 2017. Environ Sci Pollut Res Int. 24: 2620-2626. PMID: 27826830
  8. The dynamics of solvation dictates the conformation of polyethylene oxide in aqueous, isobutyric acid and binary solutions.  |  Dahal, UR. and Dormidontova, EE. 2017. Phys Chem Chem Phys. 19: 9823-9832. PMID: 28275762
  9. Gel Volume Near the Critical Point of Binary Mixture Isobutyric Acid-Water.  |  Yamamoto, T., et al. 2020. Gels. 6: PMID: 32932741
  10. Bisfunction of propionic acid on purified rat liver beta-ureidopropionase.  |  Kikugawa, M., et al. 1988. FEBS Lett. 229: 345-8. PMID: 3345846
  11. Urinary metabolites associate with the presence of diabetic kidney disease in type 2 diabetes and mediate the effect of inflammation on kidney complication.  |  Shi, C., et al. 2023. Acta Diabetol. 60: 1199-1207. PMID: 37184672
  12. Preparation of L (+) beta-hydroxyisobutyric acid by bacterial oxidation of isobutyric acid.  |  Goodhue, CT. and Schaeffer, JR. 1971. Biotechnol Bioeng. 13: 203-14. PMID: 5580680
  13. Precursor directed biosynthesis of paulomycins A and B. The effects of valine, isoleucine, isobutyric acid and 2-methylbutyric acid.  |  Marshall, VP., et al. 1984. J Antibiot (Tokyo). 37: 923-5. PMID: 6480507

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Isobutyric acid, 500 ml

sc-211667
500 ml
$41.00