Molecular structure of Iodonitrotetrazolium chloride, CAS Number: 146-68-9
Iodonitrotetrazolium chloride (CAS 146-68-9)
See product citations (6)
Alternate Names:
Iodonitrotetrazolium Chloride, p-Iodonitrotetrazolium violet
Application:
Iodonitrotetrazolium chloride is an electron acceptor that forms a formazan dye on reduction; measures dehydrogenase activity
CAS Number:
146-68-9
Molecular Weight:
505.7
Molecular Formula:
C19H13CIN5O2
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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SDS & Certificate of Analysis
Iodonitrotetrazolium chloride is an electron acceptor used in various colorimetric assays. The chemical has been mainly documented for its for measurement of dehydrogenase activity. In the assay to measure SDH (succinate dehydrogenase) activity, Iodonitrotetrazolium chloride was used as an oxidizing agent being reduced by succinate dehydrogenase. Upon reduction the compound forms a formazan dye measured at 500 nm. Iodonitrotetrazolium chloride has also been used to study the electron transport activity in soils, sediments, and pure enzyme cultures as well as nucleotide diphosphate kinase activity.
Iodonitrotetrazolium chloride (CAS 146-68-9) References
- The monitoring of nucleotide diphosphate kinase activity by blue native polyacrylamide gel electrophoresis. | Mailloux, RJ., et al. 2008. Electrophoresis. 29: 1484-9. PMID: 18324728
- Spectrophotometric determination of chromium with Iodonitrotetrazolium chloride and Tetrazolium Violet. | Kamburova, M. 1993. Talanta. 40: 707-11. PMID: 18965691
- Cysteine Potentiates Bactericidal Antibiotics Activity Against Gram-Negative Bacterial Persisters. | Liu, Y., et al. 2020. Infect Drug Resist. 13: 2593-2599. PMID: 32801796
- Susceptibility of Campylobacter Strains to Selected Natural Products and Frontline Antibiotics. | Gahamanyi, N., et al. 2020. Antibiotics (Basel). 9: PMID: 33182474
- Antibacterial secondary metabolites from Vernonia auriculifera Hiern (Asteraceae) against MDR phenotypes. | Jepkoech, C., et al. 2022. Nat Prod Res. 36: 3203-3206. PMID: 34293972
- Tetrazolium-Based Visually Indicating Bacteria Sensor for Colorimetric Detection of Point of Contamination. | Song, E., et al. 2022. ACS Appl Mater Interfaces. 14: 38153-38161. PMID: 35946791
- Bioprospecting of endophytic actinobacterium associated with Aloe ferox mill for antibacterial activity. | Maliehe, TS., et al. 2022. BMC Complement Med Ther. 22: 258. PMID: 36192707
- Chemical Profile, Antioxidant and Antibacterial Activities, Mechanisms of Action of the Leaf Extract of Aloe arborescens Mill. | Maliehe, TS., et al. 2023. Plants (Basel). 12: PMID: 36840217
- Electron transport system activity in soil, sediment, and pure cultures. | Trevors, JT. 1984. Crit Rev Microbiol. 11: 83-100. PMID: 6375976
- Assay of succinate dehydrogenase activity by a colorimetric-continuous method using iodonitrotetrazolium chloride as electron acceptor. | Munujos, P., et al. 1993. Anal Biochem. 212: 506-9. PMID: 8214593
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Iodonitrotetrazolium chloride, 1 g | sc-203739 | 1 g | $141.00 | |||
Iodonitrotetrazolium chloride, 5 g | sc-203739A | 5 g | $520.00 |