Date published: 2026-5-9

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Indanazoline (CAS 40507-78-6)

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Alternate Names:
2-(4-Indanamino)-2-imidazoline
CAS Number:
40507-78-6
Molecular Weight:
201.27
Molecular Formula:
C12H15N3
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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Indanazoline, a member of the imidazoline chemical family, serves as a potent α-adrenergic agonist. Its widespread use in scientific research stems from its capability to stimulate the sympathetic nervous system. This compound proves invaluable for exploring the physiological and biochemical repercussions of α-adrenergic receptor activation. In scientific investigations, Indanazoline fulfills a multitude of roles. It frequently functions as a research tool to delve into the physiological and biochemical impacts of α-adrenergic receptor activation. Researchers have harnessed its potential to delve into the consequences of α-adrenergic receptor activation on parameters such as blood pressure, heart rate, and vascular tone. Indanazoline has played a pivotal role in uncovering the influence of α-adrenergic receptor activation on neurotransmitter release, gene expression, and protein synthesis. Operating as a robust α-adrenergic agonist, Indanazoline binds to and triggers α-adrenergic receptors. Consequently, it initiates signaling pathways that give rise to the observed physiological and biochemical effects. Notably, Indanazoline exhibits a heightened affinity for α1-adrenergic receptors while also having some influence on α2-adrenergic receptors, albeit to a lesser extent.


Indanazoline (CAS 40507-78-6) References

  1. Nasal decongestion with imidazoline derivatives: acoustic rhinometry measurements.  |  Hochban, W., et al. 1999. Eur J Clin Pharmacol. 55: 7-12. PMID: 10206078
  2. [On the galenical development of a nose spray from N-(2-imidazolin-2-yl)-N-(4-indanyl)amine monohydrochloride (indanazoline) (author's transl)].  |  Dechow, HJ., et al. 1980. Arzneimittelforschung. 30: 1738-46. PMID: 6159899
  3. [Toxicity studies on N-(2-imidazolinew-2-yl)-N-(4-indanyl)amine monohydrochloride (indanazoline), a ne rhinologic drug].  |  Worstmann, W., et al. 1980. Arzneimittelforschung. 30: 1760-71. PMID: 6159900
  4. [Synthesis of N-(2-imidazolin-2-yl)-N-(4-indanyl)amine (indanazoline) (author's transl)].  |  May, HJ. 1980. Arzneimittelforschung. 30: 1733-7. PMID: 7192113
  5. [Pharmacology of N-(2-imidazolin-2-yl)-N-(4-indanyl)amino (indanazoline), a new vasoconstrictive imidazoline compound].  |  Kretzschmar, R., et al. 1980. Arzneimittelforschung. 30: 1746-60. PMID: 7192114

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Indanazoline, 25 mg

sc-488724
25 mg
$396.00