Molecular structure of Imipramine-2,4,6,8-d4 Hydrochloride, CAS Number: 61361-33-9
Imipramine-2,4,6,8-d4 Hydrochloride (CAS 61361-33-9)
Alternate Names:
10,11-Dihydro-N,N-dimethyl-5H-dibenz[b,f]azepine-5-propanamine-d4 Hydrochloride; Chrytemin-d4; Imiprin-d4; G-22355-d4
Application:
Imipramine-2,4,6,8-d4 Hydrochloride is an inhibitor of SLC6A2 and ST (serotonin and norepinephrine transporters)
CAS Number:
61361-33-9
Molecular Weight:
320.89
Molecular Formula:
C19H21D4ClN2
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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SDS & Certificate of Analysis
Tricyclic antidepressant that inhibits the serotonin and norepinephrine transporters and has little effect on the dopamine transporter.
Imipramine-2,4,6,8-d4 Hydrochloride (CAS 61361-33-9) References
- Locus coeruleus neuronal activity and noradrenaline availability in the frontal cortex of rats chronically treated with imipramine: effect of alpha 2-adrenoceptor blockade. | Linnér, L., et al. 1999. Biol Psychiatry. 46: 766-74. PMID: 10494444
- Inhibition of the current of heterologously expressed HERG potassium channels by imipramine and amitriptyline. | Teschemacher, AG., et al. 1999. Br J Pharmacol. 128: 479-85. PMID: 10510461
- Examination of the relationship between the uptake site for 5-hydroxytryptamine and the high affinity binding site for [3H]imipramine. II. The role of sodium ions. | Wood, MD. 1987. Neuropharmacology. 26: 1081-5. PMID: 2958719
- Disopyramide, imipramine, and amitriptyline bind to a common site on the transient outward K+ channel. | Casis, O. and Sánchez-Chapula, JA. 1998. J Cardiovasc Pharmacol. 32: 521-6. PMID: 9781919
Inhibitor of:
SLC6A2, and ST.Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Imipramine-2,4,6,8-d4 Hydrochloride, 1 mg | sc-218593 | 1 mg | $360.00 |