Date published: 2026-1-22

1-800-457-3801

SCBT Portrait Logo
Seach Input

i-Cholesteryl methyl ether (CAS 2867-93-8)

0.0(0)
Write a reviewAsk a question

Alternate Names:
3α,5-Cyclo-5α-cholestan-6β-ol methyl ether, 6β-Methoxy-3α,5-cyclocholestane
CAS Number:
2867-93-8
Molecular Weight:
400.68
Molecular Formula:
C28H48O
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

QUICK LINKS

i-Cholesteryl methyl ether is a compound that functions as a cholesterol analog in experimental applications. It is used to investigate the interactions of cholesterol and its derivatives with various biological systems. i-Cholesteryl methyl ether is known to mimic the behavior of cholesterol in cellular membranes. i-Cholesteryl methyl ether interacts with membrane proteins and lipid bilayers, influencing their organization and dynamics. By serving as a cholesterol surrogate, i-Cholesteryl methyl ether enables insights into the role of cholesterol in cellular processes without directly using cholesterol itself. I-Cholesteryl Methyl Ether′s mechanism of action involves modulating membrane properties and influencing the behavior of cholesterol-dependent proteins, making it useful for studying the impact of cholesterol on biological systems.


i-Cholesteryl methyl ether (CAS 2867-93-8) References

  1. Mechanism of formation of cholesterylisothiuronium salts from i-cholesteryl methyl ether.  |  PEARSON, RG., et al. 1948. J Am Chem Soc. 70: 3479-81. PMID: 18891899
  2. Exchange at the 6-position of i-cholesteryl methyl ether.  |  WINSTEIN, S. and SCHLESINGER, AH. 1948. J Am Chem Soc. 70: 3528. PMID: 18933573
  3. Sphingolipid domains in the plasma membranes of fibroblasts are not enriched with cholesterol.  |  Frisz, JF., et al. 2013. J Biol Chem. 288: 16855-16861. PMID: 23609440
  4. Hemagglutinin clusters in the plasma membrane are not enriched with cholesterol and sphingolipids.  |  Wilson, RL., et al. 2015. Biophys J. 108: 1652-1659. PMID: 25863057
  5. Optimised conditions for the synthesis of (17)O and (18)O labelled cholesterol.  |  de la Calle Arregui, C., et al. 2016. Chem Phys Lipids. 195: 58-62. PMID: 26724708
  6. Detection in extracts of bovine brain of lipophilic complexes of sulfate esters of cholesterol and beta-sitosterol.  |  Prasad, VV., et al. 1985. Proc Natl Acad Sci U S A. 82: 2657-9. PMID: 3857607

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

i-Cholesteryl methyl ether, 250 mg

sc-215163
250 mg
$22.00