Molecular structure of Hydroxyguanidine sulfate, CAS Number: 13115-21-4
Hydroxyguanidine sulfate (CAS 13115-21-4)
CAS Number:
13115-21-4
Molecular Weight:
124.11
Molecular Formula:
CH5N3O•0.5H2SO4
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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Hydroxyguanidine sulfate is a substrate found in endothelial cells that reacts with nitric oxide to produce a vasodilating compound. Suppression of this reaction occurs when oxyhaemoglobin is present. In addition, the actions of hydroxyguanidine sulfate is similar to NG-hydroxy-L-arginine resulting in the stabilization and potentiation of nitric oxide. Hydroxyguanidine serves as a specific reduction cosubstrate for the enzyme dopamine β-hydroxylase, used in the conversion of the neurotransmitter dopamine into norepinephrine.
Hydroxyguanidine sulfate (CAS 13115-21-4) References
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- Nitric oxide and another potent vasodilator are formed from NG-hydroxy-L-arginine by cultured endothelial cells. | Zembowicz, A., et al. 1991. Proc Natl Acad Sci U S A. 88: 11172-6. PMID: 1662386
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- Antitumor activity of amidoximes (hydroxyurea analogs) in murine tumor systems. | Flora, KP., et al. 1978. Cancer Res. 38: 1291-5. PMID: 639062
- Synthesis and testing of new antileukemic Schiff bases of N-hydroxy-N'-aminoguanidine against CCRF-CEM/0 human leukemia cells in vitro and synergism studies with cytarabine (Ara-C). | Koneru, PB., et al. 1993. Pharm Res. 10: 515-20. PMID: 8483833
- Highly Salt-tolerant hydrogen evolution reaction based on dendritic urchin-like MoC/MoS2 heterojunction in seawater | Wenpeng Wu a, Xinqun Zhang a, Yukun Xiao a, Zhihua Cheng b, Tian Yang a, Jinsheng Lv a, Man Yuan a, Jiajia Liu a, Yang Zhao a. 2024. Chemical Engineering Journal. 480.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Hydroxyguanidine sulfate, 5 mg | sc-200341 | 5 mg | $60.00 | |||
Hydroxyguanidine sulfate, 25 mg | sc-200341A | 25 mg | $300.00 |