HUV-EC-C Whole Cell Lysate: sc-364180

HUV-EC-C Whole Cell Lysate is derived from the HUV-EC-C cell line, which consists of human umbilical vein endothelial cells (HUVECs). These cells are isolated from the endothelial layer of veins found in the umbilical cord and are commonly used in biological research due to their central role in vascular biology. The lysate is produced by lysing HUV-EC-C cells, a process that involves disrupting the cell membranes to release a comprehensive array of cellular components, such as proteins, nucleic acids, enzymes, and small metabolites. This mixture provides a snapshot of the cellular environment and is pivotal for studying cellular mechanisms in endothelial cells, particularly how these cells interact with their microenvironment, respond to various stimuli, and maintain vascular integrity. Researchers utilize HUV-EC-C Whole Cell Lysate to explore fundamental biological processes like angiogenesis, endothelial cell migration, and the effects of various cytokines or growth factors on endothelial physiology. By analyzing such lysates, researchers can gain insights into the signaling pathways active in endothelial cells and how these pathways contribute to the functioning of vascular systems, aiding in the understanding of vascular development and the maintenance of vascular health.

HUV-EC-C Whole Cell Lysate References:

1. Age, sex, and regional differences in scavenger receptor CD36 in the mouse brain: Potential relevance to cerebral amyloid angiopathy and Alzheimer′s disease.  |  Edler, MK., et al. 2021. J Comp Neurol. 529: 2209-2226. PMID: 33319367