Date published: 2026-2-6

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HSV-2 gC Antibody (H1196): sc-69801

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Datasheets
  • HSV-2 gC Antibody (H1196) is a mouse monoclonal IgG2a HSV-2 gC antibody, cited in 3 publications, provided at 100 µg/ml
  • raised against HSV-2
  • recommended for detection of gC of HSV-2 origin by WB and IF
  • At present, we have not yet completed the identification of the preferred secondary detection reagent(s) for HSV-2 gC Antibody (H1196). This work is in progress.
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HSV-2 gC Antibody (H1196) is a mouse monoclonal IgG2a antibody that detects HSV-2 gC protein by western blotting (WB) and immunofluorescence (IF). Anti-HSV-2 gC antibody (H1196) is available as non-conjugated format, providing researchers with a reliable tool for studying this critical viral protein. Herpes simplex virus 2 (HSV-2) is known for causing genital herpes, a condition that leads to significant discomfort and impacts sexual health. HSV-2 gC protein plays a vital role in viral immune evasion by binding to complement component C3b, effectively inhibiting complement-mediated neutralization and allowing viral persistence in the host. This immune evasion enables viral survival and replication, particularly during asymptomatic periods when HSV-2 remains dormant in nerve cells. Understanding HSV-2 gC function and immune system interactions can provide insights into potential therapeutic targets and strategies for managing HSV infections.

For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.

Alexa Fluor® is a trademark of Molecular Probes Inc., OR., USA

LI-COR® and Odyssey® are registered trademarks of LI-COR Biosciences

HSV-2 gC Antibody (H1196) References:

  1. Monoclonal antibodies suitable for type-specific identification of herpes simplex viruses by a rapid culture assay.  |  Bystrická, M., et al. 1999. Acta Virol. 43: 399-402. PMID: 10825932
  2. Herpes simplex virus type 1-encoded glycoprotein C enhances coagulation factor VIIa activity on the virus.  |  Sutherland, MR., et al. 2004. Thromb Haemost. 92: 947-55. PMID: 15543320
  3. Efficient replication by herpes simplex virus type 1 involves activation of the IkappaB kinase-IkappaB-p65 pathway.  |  Gregory, D., et al. 2004. J Virol. 78: 13582-90. PMID: 15564469
  4. Production of herpes B virus recombinant glycoproteins and evaluation of their diagnostic potential.  |  Perelygina, L., et al. 2005. J Clin Microbiol. 43: 620-8. PMID: 15695655
  5. Implications for herpes simplex virus vaccine strategies based on antibodies produced to herpes simplex virus type 1 glycoprotein gC immune evasion domains.  |  Chang, YJ., et al. 2005. Vaccine. 23: 4658-65. PMID: 15936852
  6. Herpes simplex virus type 1-encoded glycoprotein C contributes to direct coagulation factor X-virus binding.  |  Livingston, JR., et al. 2006. Biochem J. 393: 529-35. PMID: 16212554
  7. Herpes simplex virus type 1 and 2 glycoprotein C prevents complement-mediated neutralization induced by natural immunoglobulin M antibody.  |  Hook, LM., et al. 2006. J Virol. 80: 4038-46. PMID: 16571820
  8. Type-common and type-specific monoclonal antibodies to herpes simplex virus types 1 and 2.  |  Bystrická, M., et al. 1991. Acta Virol. 35: 152-64. PMID: 1681713
  9. Monoclonal antibodies to the distinct antigenic sites on glycoproteins C and B and their protective abilities in herpes simplex virus infection.  |  Bystrická, M., et al. 1997. Acta Virol. 41: 5-12. PMID: 9199708

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

HSV-2 gC Antibody (H1196)

sc-69801
100 µg/ml
$322.00

What is the total volume provided of HSV-2 gC (H1196): sc-69801 monoclonal antibody?

Asked by: TinTin
Thank you for your question. This antibody is provided as 100 µg in 1 ml total volume.
Answered by: Technical Support
Date published: 2017-03-07
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Rated 5 out of 5 by from Good for Western BlotThis antibody has been used for detection of HSV-2 gC by Western Blot in published research. -SCBT QC
Date published: 2023-09-14
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HSV-2 gC Antibody (H1196) is rated 3.5 out of 5 by 2.
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