HLA-F Antibody (201A2J): sc-517641

HLA-F Antibody (201A2J) is a mouse monoclonal IgG1 antibody that detects HLA-F in human samples through western blotting (WB). HLA-F, also known as CDA12 or HLA-5.4, is a 346 amino acid single-pass type I membrane protein that plays a crucial role in the immune response by functioning as a receptor for presenting peptides to T lymphocytes. HLA-F is primarily located on the surface of cells, where HLA-F binds to specific peptides derived from intracellular proteins, facilitating the recognition of infected or abnormal cells by the immune system. HLA-F expression is particularly important as HLA-F can influence the activation and differentiation of T cells, thereby impacting the overall immune response. Additionally, HLA-F is known to interact with other proteins within the MHC class I family, which can further modulate immune signaling pathways. The unique structural properties of HLA-F, along with HLA-F interactions, underscore HLA-F significance in maintaining immune homeostasis and responding to pathogenic challenges. Anti-HLA-F antibody (201A2J) is an essential tool for researchers studying the complexities of immune responses and the role of MHC molecules in health and disease.

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