HEATR9 Antibody (G-6): sc-398998
- HEATR9 Antibody (G-6) is a mouse monoclonal IgG1 κ HEATR9 antibody provided at 200 µg/ml
- specific for an epitope mapping between amino acids 74-93 within an internal region of HEATR9 of human origin
- HEATR9 Antibody (G-6) is recommended for detection of HEATR9 of human origin by WB, IP, IF and ELISA
- Anti-HEATR9 Antibody (G-6) is available conjugated to agarose for IP; HRP for WB, IHC(P) and ELISA; and to either phycoerythrin or FITC for IF, IHC(P) and FCM
- also available conjugated to Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 or Alexa Fluor® 647 for WB (RGB), IF, IHC(P) and FCM, and for use with RGB fluorescent imaging systems, such as iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- also available conjugated to Alexa Fluor® 680 or Alexa Fluor® 790 for WB (NIR), IF and FCM; for use with Near-Infrared (NIR) detection systems, such as LI-COR®Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- m-IgG Fc BP-HRP and m-IgG1 BP-HRP are the preferred secondary detection reagents for HEATR9 Antibody (G-6) for WB applications. These reagents are now offered in bundles with HEATR9 Antibody (G-6) (see ordering information below).
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HEATR9 Antibody (G-6) is a mouse monoclonal IgG1 kappa light chain antibody that detects HEATR9 protein of human origin by western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). HEATR9 (G-6) antibody is available in both non-conjugated and various conjugated forms, including agarose, horseradish peroxidase (HRP), phycoerythrin (PE), fluorescein isothiocyanate (FITC), and multiple Alexa Fluor® conjugates. HEATR9 plays a crucial role in cellular processes, particularly in the regulation of gene expression and RNA metabolism, which are essential for maintaining cellular homeostasis and responding to stress. HEATR9 function is vital, as dysregulation has been implicated in various diseases, including cancer, where HEATR9 may influence tumor progression and response to therapy. Understanding HEATR9 function is important for developing targeted therapies and improving patient outcomes. Chromosome 17, where HEATR9 is located, houses over 1,200 genes, including key tumor suppressor genes like p53 and BRCA1, which are critical for DNA repair and maintaining genetic integrity. HEATR9 interaction with these tumor suppressors highlights HEATR9′s importance in cancer biology and potential as a therapeutic target.
Alexa Fluor® is a trademark of Molecular Probes Inc., OR., USA
LI-COR® and Odyssey® are registered trademarks of LI-COR Biosciences
HEATR9 Antibody (G-6) References:
- Birt-Hogg-Dubé Syndrome. | Welsch, MJ., et al. 2005. Int J Dermatol. 44: 668-73. PMID: 16101870
- BLIMP1 regulates cell growth through repression of p53 transcription. | Yan, J., et al. 2007. Proc Natl Acad Sci U S A. 104: 1841-6. PMID: 17264218
- Neurofibromatosis 1, and Not TP53, seems to be the main target of chromosome 17 deletions in de novo acute myeloid leukemia. | Suela, J., et al. 2007. J Clin Oncol. 25: 1151-2; author reply 1152-3. PMID: 17369586
- Quantification of N-acetylaspartic acid in urine by LC-MS/MS for the diagnosis of Canavan disease. | Al-Dirbashi, OY., et al. 2007. J Inherit Metab Dis. 30: 612. PMID: 17632691
- Susceptibility to breast cancer: hereditary syndromes and low penetrance genes. | Nusbaum, R., et al. Breast Dis. 27: 21-50. PMID: 17917139
- Genetic causes of brain tumors: neurofibromatosis, tuberous sclerosis, von Hippel-Lindau, and other syndromes. | Farrell, CJ. and Plotkin, SR. 2007. Neurol Clin. 25: 925-46, viii. PMID: 17964021
- Breast cancer risk among male BRCA1 and BRCA2 mutation carriers. | Tai, YC., et al. 2007. J Natl Cancer Inst. 99: 1811-4. PMID: 18042939
- Novel deletion mutation in GFAP gene in an infantile form of Alexander disease. | Murakami, N., et al. 2008. Pediatr Neurol. 38: 50-2. PMID: 18054694
- Strategies for ovarian cancer prevention. | Dann, RB., et al. 2007. Obstet Gynecol Clin North Am. 34: 667-86, viii. PMID: 18061863
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
HEATR9 Antibody (G-6) | sc-398998 | 200 µg/ml | $316.00 | |||
HEATR9 Antibody (G-6): m-IgG Fc BP-HRP Bundle | sc-527840 | 200 µg Ab; 10 µg BP | $354.00 | |||
HEATR9 Antibody (G-6): m-IgG1 BP-HRP Bundle | sc-533213 | 200 µg Ab; 20 µg BP | $354.00 | |||
HEATR9 Antibody (G-6) AC | sc-398998 AC | 500 µg/ml, 25% agarose | $416.00 | |||
HEATR9 Antibody (G-6) HRP | sc-398998 HRP | 200 µg/ml | $316.00 | |||
HEATR9 Antibody (G-6) FITC | sc-398998 FITC | 200 µg/ml | $330.00 | |||
HEATR9 Antibody (G-6) PE | sc-398998 PE | 200 µg/ml | $343.00 | |||
HEATR9 Antibody (G-6) Alexa Fluor® 488 | sc-398998 AF488 | 200 µg/ml | $357.00 | |||
HEATR9 Antibody (G-6) Alexa Fluor® 546 | sc-398998 AF546 | 200 µg/ml | $357.00 | |||
HEATR9 Antibody (G-6) Alexa Fluor® 594 | sc-398998 AF594 | 200 µg/ml | $357.00 | |||
HEATR9 Antibody (G-6) Alexa Fluor® 647 | sc-398998 AF647 | 200 µg/ml | $357.00 | |||
HEATR9 Antibody (G-6) Alexa Fluor® 680 | sc-398998 AF680 | 200 µg/ml | $357.00 | |||
HEATR9 Antibody (G-6) Alexa Fluor® 790 | sc-398998 AF790 | 200 µg/ml | $357.00 | |||
HEATR9 (G-6) Neutralizing Peptide | sc-398998 P | 100 µg/0.5 ml | $68.00 |