Molecular structure of Guanethidine Hemisulfate, CAS Number: 60-02-6
Guanethidine Hemisulfate (CAS 60-02-6)
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Application:
Guanethidine Hemisulfate is a compound also known as 2-(1′-Azacyclooctyl)ethylguanidine Hemisulfate
CAS Number:
60-02-6
Molecular Weight:
247.35
Molecular Formula:
C10H22N4•1/2H2SO4
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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SDS & Certificate of Analysis
Guanethidine Hemisulfate has been extensively studied in scientific research for its ability to lower blood pressure. It blocks the release of norepinephrine from sympathetic nerve endings. Norepinephrine is a hormone that constricts blood vessels and increases blood pressure. By blocking its release, Guanethidine Hemisulfate causes blood vessels to relax and blood pressure to decrease. It also decreases heart rate and cardiac output, which further reduces blood pressure.
Guanethidine Hemisulfate (CAS 60-02-6) References
- The reassertion profiles of long acting β2-adrenoceptor agonists in the guinea pig isolated trachea and human recombinant β2-adrenoceptor. | Patel, S., et al. 2011. Pulm Pharmacol Ther. 24: 247-55. PMID: 21134482
- Perspective on the role of P2X-purinoceptor activation in human vas deferens contractility. | Amobi, NI., et al. 2012. Exp Physiol. 97: 583-602. PMID: 22227201
- Glycogen shortage during fasting triggers liver-brain-adipose neurocircuitry to facilitate fat utilization. | Izumida, Y., et al. 2013. Nat Commun. 4: 2316. PMID: 23939267
- Autonomic nervous system-mediated effects of galanin-like peptide on lipid metabolism in liver and adipose tissue. | Hirako, S., et al. 2016. Sci Rep. 6: 21481. PMID: 26892462
- Steric aspects of adrenergic drugs. XXII. Retention of (+)- and (-)- 14 C-norepinephrine by mouse heart. | Garg, BD., et al. 1973. J Pharm Sci. 62: 1126-9. PMID: 4145954
- Presynaptic dual inhibitory actions of guanabenz on adrenergic transmission. | Misu, Y., et al. 1982. Eur J Pharmacol. 77: 177-81. PMID: 6277662
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Guanethidine Hemisulfate, 250 mg | sc-295027A | 250 mg | $156.00 | |||
Guanethidine Hemisulfate, 1 g | sc-295027 | 1 g | $250.00 | |||
Guanethidine Hemisulfate, 2 g | sc-295027B | 2 g | $510.00 | |||
Guanethidine Hemisulfate, 5 g | sc-295027C | 5 g | $1098.00 | |||
Guanethidine Hemisulfate, 10 g | sc-295027D | 10 g | $1997.00 |