GSTM4 Antibody (PL-B12): sc-134353
- GSTM4 Antibody (PL-B12) is a mouse monoclonal IgG2a κ GSTM4 antibody, cited in 1 publications, provided at 100 µg/ml
- raised against recombinant GSTM4 protein of human origin
- recommended for detection of GSTM4 of human origin by WB, IP and ELISA
- At present, we have not yet completed the identification of the preferred secondary detection reagent(s) for GSTM4 Antibody (PL-B12). This work is in progress.
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GSTM4 Antibody (PL-B12) is a mouse monoclonal IgG2a kappa light chain antibody that detects GSTM4 protein of human origin by western blotting (WB), immunoprecipitation (IP), and enzyme-linked immunosorbent assay (ELISA). Anti-GSTM4 antibody (PL-B12) is available as a non-conjugated format, providing researchers with a reliable tool for studying this important protein. GSTM4 plays a crucial role in the detoxification process, specifically by conjugating with glutathione to neutralize harmful substances, including carcinogens and environmental toxins. This function is vital for cellular protection against oxidative stress and toxicant-induced damage, making GSTM4 a key player in maintaining cellular health and preventing disease. As a member of the mu class of glutathione S-transferases, GSTM4 is part of a larger family of eight GST protein families, each contributing to various cellular functions. Understanding GSTM4 and its interactions with other proteins can provide insights into its significance in detoxification pathways and potential implications in cancer research and therapeutic development.
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GSTM4 Antibody (PL-B12) References:
- A T2517C polymorphism in the GSTM4 gene is associated with risk of developing lung cancer. | Liloglou, T., et al. 2002. Lung Cancer. 37: 143-6. PMID: 12140136
- Screening for inter-individual splicing differences in human GSTM4 and the discovery of a single nucleotide substitution related to the tandem skipping of two exons. | Denson, J., et al. 2006. Gene. 379: 148-55. PMID: 16854533
- Constitutive mRNA expression of various glutathione S-transferase isoforms in different tissues of mice. | Knight, TR., et al. 2007. Toxicol Sci. 100: 513-24. PMID: 17890767
- Structure of human glutathione S-transferase class Mu genes. | Taylor, JB., et al. 1991. Biochem J. 274 (Pt 2): 587-93. PMID: 2006920
- Chromosomal mapping of the human Mu class glutathione S-transferases to 1p13. | Ross, VL., et al. 1993. Genomics. 18: 87-91. PMID: 8276420
- Isolation and analysis of the gene and cDNA for a human Mu class glutathione S-transferase, GSTM4. | Comstock, KE., et al. 1993. J Biol Chem. 268: 16958-65. PMID: 8349586
- Molecular cloning and heterologous expression of an alternatively spliced human Mu class glutathione S-transferase transcript. | Ross, VL. and Board, PG. 1993. Biochem J. 294 (Pt 2): 373-80. PMID: 8373352
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
GSTM4 Antibody (PL-B12) | sc-134353 | 100 µg/ml | $333.00 |