Gram Positive Bacteria Marker Antibody (BDI380): sc-57752

Gram Positive Bacteria Marker Antibody (BDI380) is a mouse monoclonal IgG1 antibody that detects lipoteichoic acid (LTA) of Gram Positive Bacteria origin by immunofluorescence (IF) and enzyme-linked immunosorbent assay (ELISA). Anti-Gram Positive Bacteria Marker antibody (BDI380) is available as the non-conjugated format. The presence of lipoteichoic acid is crucial as LTA plays a significant role in the structural integrity of the bacterial cell wall and is involved in various cellular processes, including cell division and adherence to host tissues. This component not only contributes to the rigidity of the cell wall but also serves as a key factor in the pathogenicity of Gram-positive bacteria, influencing their ability to evade the host immune response. Gram-positive bacteria, which retain a crystal violet dye during the Gram staining process, appear blue or violet under a microscope, distinguishing them from Gram-negative bacteria that appear red or pink. The thicker layer of peptidoglycan in their cell walls is essential for maintaining cell shape and protecting against environmental stress. Major groups of Gram-positive bacteria include genera such as Bacillus, Listeria, Staphylococcus, Streptococcus, Enterococcus, and Clostridium, as well as the phylum Actinobacteria. Gram Positive Bacteria Marker (BDI380) antibody is instrumental in studying the function and behavior of these bacteria, providing valuable insights into their biology and potential pathogenic mechanisms.

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Gram Positive Bacteria Marker Antibody (BDI380) References:

1. Conserved anchoring mechanisms between crystalline cell surface S-layer proteins and secondary cell wall polymers in Gram-positive bacteria?  |  Sára, M. 2001. Trends Microbiol. 9: 47-9; discussion 49-50. PMID: 11173224
2. Characteristics of surfactant protein A and D binding to lipoteichoic acid and peptidoglycan, 2 major cell wall components of gram-positive bacteria.  |  van de Wetering, JK., et al. 2001. J Infect Dis. 184: 1143-51. PMID: 11598837
3. Mercuric reductase in environmental gram-positive bacteria sensitive to mercury.  |  Bogdanova, ES., et al. 1992. FEMS Microbiol Lett. 76: 95-100. PMID: 1427009
4. Protein sorting to the cell wall envelope of Gram-positive bacteria.  |  Ton-That, H., et al. 2004. Biochim Biophys Acta. 1694: 269-78. PMID: 15546671
5. The structure of secondary cell wall polymers: how Gram-positive bacteria stick their cell walls together.  |  Schäffer, C. and Messner, P. 2005. Microbiology (Reading). 151: 643-651. PMID: 15758211
6. Unusual compound present in cell walls of streptomycin-dependent strains of some gram-positive bacteria.  |  Lawrence, NL. and Scruggs, ME. 1966. J Bacteriol. 91: 1378-9. PMID: 4956336
7. Heterogenetic antigens of gram-positive bacteria.  |  Chorpenning, FW. and Dodd, MC. 1966. J Bacteriol. 91: 1440-5. PMID: 4956340
8. Composition of the membranes isolated from several Gram-positive bacteria.  |  Salton, MR. and Freer, JH. 1965. Biochim Biophys Acta. 107: 531-8. PMID: 5867308
9. Cell walls, peptidoglycans, and teichoic acids of Gram-positive bacteria as polyclonal inducers and immunomodulators of proliferative and lymphokine responses of human B and T lymphocytes.  |  Räsänen, L. and Arvilommi, H. 1982. Infect Immun. 35: 523-7. PMID: 6799405

Monoclonal antibodies for mammalian and non-mammalian protein targets represent essentially all targets covered by polyclonal antibodies. Over 8,300 of our antibodies are offered as ImmunoCruz^® conjugates which eliminates the need for a secondary antibody.

Santa Cruz Biotechnology antibodies have over 360,000 research citations. Anti-Gram Positive Bacteria Marker Antibody (BDI380) has 3 citations in a variety of scientific publications.

Primary antibodies for mammalian target proteins are recommended for the detection of a range of mammalian species, primarily of mouse, rat and human species. Many mammalian antibodies are also ideal for veterinary research and reactive with ovine, porcine, caprine, feline, canine, bovine and equine protein targets. Santa Cruz Biotechnology primary monoclonal antibodies are suitable for laboratory research applications and are not intended for diagnostic or therapeutic use.

Gram Positive Bacteria Marker Antibody (BDI380) Specifications

Alternate Product Name: Gram Positive Bacteria Marker

Product Clone Name: BDI380

Classification: Primary Antibody

Clonality: Monoclonal Antibody

Antibody Isotype: IgG₁

Amino Acids:

Epitope Target: Gram Positive Bacteria Marker

Epitope Species: Gram-positive bacteria

Product Reactivity/Detection: lipoteichoic acid (LTA)

Species Reactivity/Detection: Gram Positive Bacteria

Additional Mammalian Reactivity: N/A

Additional Non-Mammalian Reactivity: N/A

Applications: IF, ELISA

Vialing Information: Each vial contains 100 µg IgG₁ in 1.0 ml of PBS with < 0.1% sodium azide and 0.1% gelatin

Research Citations: 3 citations in various scientific publications

Available Conjugates/Forms for Gram Positive Bacteria Marker Antibody (BDI380): N/A