Date published: 2026-5-25

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GNPDA1 Antibody (237CT2.5.2): sc-517332

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  • GNPDA1 Antibody (237CT2.5.2) is a mouse monoclonal IgG1 κ GNPDA1 antibody provided at 100 µg/ml
  • raised against a recombinant protein corresponding to GNPDA1 of human origin
  • recommended for detection of GNPDA1 of mouse, rat and human origin by WB and IP
  • At present, we have not yet completed the identification of the preferred secondary detection reagent(s) for GNPDA1 Antibody (237CT2.5.2). This work is in progress.
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    GNPDA1 Antibody (237CT2.5.2) is a mouse monoclonal IgG1 kappa light chain antibody that detects GNPDA1 protein of mouse, rat, and human origin by western blotting (WB) and immunoprecipitation (IP). Anti-GNPDA1 antibody (237CT2.5.2) is available as a non-conjugated format. GNPDA1 (237CT2.5.2) antibody recognizes a protein that plays a crucial role in cellular metabolism, specifically in the conversion of glucosamine-6-phosphate to fructose-6-phosphate and ammonia, which is essential for proper functioning of various metabolic pathways. GNPDA1 monoclonal antibody (237CT2.5.2) targets a protein that is abundantly expressed in tissues with high metabolic demands, such as testis, ovary, and heart. GNPDA1 exists as a homohexamer, which is vital for enzymatic function, and activity is regulated by various factors, including post-translational modifications that influence stability and protein interactions. Understanding GNPDA1′s function and regulation is important for elucidating its role in reproductive biology and metabolic disorders, making anti-GNPDA1 antibody (237CT2.5.2) a valuable research tool.

    For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.

    Alexa Fluor® is a trademark of Molecular Probes Inc., OR., USA

    LI-COR® and Odyssey® are registered trademarks of LI-COR Biosciences

    GNPDA1 Antibody (237CT2.5.2) References:

    1. Characterization of testicular mouse glucosamine 6-phosphate deaminase (GNPDA).  |  Montag, M., et al. 1999. FEBS Lett. 458: 141-4. PMID: 10481053
    2. Cloning, sequencing, and expression analysis of mouse glucosamine-6-phosphate deaminase (GNPDA/oscillin).  |  Amireault, P. and Dubé, F. 2000. Mol Reprod Dev. 56: 424-35. PMID: 10862010
    3. Cloning and functional characterization of GNPI2, a novel human homolog of glucosamine-6-phosphate isomerase/oscillin.  |  Zhang, J., et al. 2003. J Cell Biochem. 88: 932-40. PMID: 12616532
    4. Phlegm-dampness constitution: genomics, susceptibility, adjustment and treatment with traditional Chinese medicine.  |  Wang, J., et al. 2013. Am J Chin Med. 41: 253-62. PMID: 23548117
    5. Identification of differential proteins in colorectal cancer cells treated with caffeic acid phenethyl ester.  |  He, YJ., et al. 2014. World J Gastroenterol. 20: 11840-9. PMID: 25206290
    6. Hexosamine biosynthesis in keratinocytes: roles of GFAT and GNPDA enzymes in the maintenance of UDP-GlcNAc content and hyaluronan synthesis.  |  Oikari, S., et al. 2016. Glycobiology. 26: 710-22. PMID: 26887390
    7. Glucosamine-6-Phosphate Isomerase 1 Promotes Tumor Progression and Indicates Poor Prognosis in Hepatocellular Carcinoma.  |  Li, D., et al. 2020. Cancer Manag Res. 12: 4923-4935. PMID: 32606980
    8. The Possible Roles of Glucosamine-6-Phosphate Deaminases in Ammonium Metabolism in Cancer.  |  Lara-Lemus, R., et al. 2024. Int J Mol Sci. 25: PMID: 39596123
    9. Calcium oscillations in mammalian eggs triggered by a soluble sperm protein.  |  Parrington, J., et al. 1996. Nature. 379: 364-8. PMID: 8552195
    10. Molecularly cloned mammalian glucosamine-6-phosphate deaminase localizes to transporting epithelium and lacks oscillin activity.  |  Wolosker, H., et al. 1998. FASEB J. 12: 91-9. PMID: 9438414
    11. A novel protein for Ca2+ signaling at fertilization.  |  Parrington, J., et al. 1998. Curr Top Dev Biol. 39: 215-43. PMID: 9476002
    12. The human glucosamine-6-phosphate deaminase gene: cDNA cloning and expression, genomic organization and chromosomal localization.  |  Shevchenko, V., et al. 1998. Gene. 216: 31-8. PMID: 9714720

    Ordering Information

    Product NameCatalog #UNITPriceQtyFAVORITES

    GNPDA1 Antibody (237CT2.5.2)

    sc-517332
    100 µg/ml
    $322.00