Date published: 2025-12-5

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Glycidyltrimethylammonium chloride (CAS 3033-77-0)

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Alternate Names:
(2,3-Epoxypropyl)trimethylammonium chloride
CAS Number:
3033-77-0
Purity:
≥90%
Molecular Weight:
151.63
Molecular Formula:
C6H14ClNO
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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Glycidyltrimethylammonium chloride is a quaternary ammonium compound that functions as a cationic monomer in polymerization reactions. Its mechanism of action involves the formation of covalent bonds with other monomers, leading to the production of cationic polymers with high molecular weight. Glycidyltrimethylammonium Chloride′s functional role is to facilitate the polymerization process by providing a positively charged moiety that can interact with negatively charged species, leading to the formation of stable polymeric structures. In experimental applications, it acts as a reactive intermediate in the synthesis of cationic polymers, enabling the modification of surface properties and the development of materials with specific functionalities.


Glycidyltrimethylammonium chloride (CAS 3033-77-0) References

  1. alpha,beta-poly(asparthylhydrazide)-glycidyltrimethylammonium chloride copolymers (PAHy-GTA): novel polymers with potential for DNA delivery.  |  Pedone, E., et al. 2001. J Control Release. 77: 139-53. PMID: 11689267
  2. Derivatization of small oligosaccharides prior to analysis by matrix-assisted laser desorption/ionization using glycidyltrimethylammonium chloride and Girard's reagent T.  |  Gouw, JW., et al. 2002. Rapid Commun Mass Spectrom. 16: 905-12. PMID: 11968119
  3. Dextran-glycidyltrimethylammonium chloride conjugate/DNA nanoplex: A potential non-viral and haemocompatible gene delivery system.  |  Thomas, JJ., et al. 2010. Int J Pharm. 389: 195-206. PMID: 20080161
  4. Synthesis and rheological characterization of water-soluble glycidyltrimethylammonium-chitosan.  |  Rwei, SP., et al. 2014. Mar Drugs. 12: 5547-62. PMID: 25419996
  5. Biobased monoliths for adenovirus purification.  |  Fernandes, CS., et al. 2015. ACS Appl Mater Interfaces. 7: 6605-12. PMID: 25756920
  6. Phosphorylated-CNC/modified-chitosan nanocomplexes for the stabilization of Pickering emulsions.  |  Baek, J., et al. 2019. Carbohydr Polym. 206: 520-527. PMID: 30553353
  7. Development of Synergistic Antimicrobial Coating of p-Aramid Fibers Using Ag Nanoparticles and Glycidyltrimethylammonium Chloride (GTAC) without the Aid of a Cross-Linking Agent.  |  Kang, C., et al. 2017. Polymers (Basel). 9: PMID: 30971033
  8. Production of aminated peat from branched polyethylenimine and glycidyltrimethylammonium chloride for sulphate removal from mining water.  |  Gogoi, H., et al. 2019. Environ Res. 175: 323-334. PMID: 31150931
  9. One-pot preparation of zwitterion-type lignin polymers.  |  Guo, Y., et al. 2019. Int J Biol Macromol. 140: 429-440. PMID: 31425764
  10. Genotoxic effects of glycidyltrimethylammonium chloride.  |  Vleminckx, C., et al. 1987. Mutat Res. 189: 387-94. PMID: 3317031
  11. Amphiphilic quaternized chitosan: Synthesis, characterization, and anti-cariogenic biofilm property.  |  Phuangkaew, T., et al. 2022. Carbohydr Polym. 277: 118882. PMID: 34893285
  12. Development of Quaternized Chitosan Integrated with Nanofibrous Polyacrylonitrile Mat as an Anion-Exchange Membrane.  |  Akhmetova, A., et al. 2022. ACS Omega. 7: 45371-45380. PMID: 36530230
  13. Efficient Cationization of Cotton for Salt-Free Dyeing by Adjusting Fiber Crystallinity through Alcohol-Water-NaOH Pretreatment.  |  Wu, A., et al. 2022. Polymers (Basel). 14: PMID: 36559913

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Glycidyltrimethylammonium chloride, 50 ml

sc-235263
50 ml
$66.00

Glycidyltrimethylammonium chloride, 250 ml

sc-235263A
250 ml
$215.00