Glycerophospho-N-Palmitoyl Ethanolamine (CAS 100575-09-5)
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N-Acylated ethanolamines (NAE) are naturally-occurring lipids that have diverse bioactivities. For example, arachidonoyl ethanolamide (AEA) is an endogenous neurotransmitter that evokes cellular responses by activating the cannabinoid receptors, peripheral cannabinoid (CB2) and central cannabinoid (CB1). The different types of NAE are derived from glycerophospho-linked precursors by the activity of glycerophosphodiesterase 1 (GDE1) (1). Glycerophospho-N-palmitoyl ethanolamine (GP-NPEA) is the metabolic precursor of palmitoyl ethanolamide (PEA). PEA is an endogenous CB found in liver, brain, and other mammalian tissues, (2) that has potent anti-inflammatory activity in vivo (3). PEA has no appreciable affinity for CB1 and low affinity for CB2 (4) suggesting that its efficacy is through a different receptor.
Glycerophospho-N-Palmitoyl Ethanolamine (CAS 100575-09-5) References
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Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Glycerophospho-N-Palmitoyl Ethanolamine, 1 mg | sc-224009 | 1 mg | $63.00 | |||
Glycerophospho-N-Palmitoyl Ethanolamine, 5 mg | sc-224009A | 5 mg | $379.00 |