Glutaconic acid (CAS 1724-02-3)
Alternate Names:
2-Pentenedioic acid
CAS Number:
1724-02-3
Molecular Weight:
130.10
Molecular Formula:
C5H6O4
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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Glutaconic acid, a naturally occurring organic compound with the molecular formula C5H6O4, belongs to the aconitic acid family as an unsaturated dicarboxylic acid. It is naturally present in various plants, including the red maple tree′s bark. Its applications in scientific studies encompass investigating oxidative stress′s impact on cells, exploring the effects of environmental pollutants, examining cancer cells′ response to chemotherapy, assessing the influence of specific drugs and hormones on the body, and more. Glutaconic acid exhibits diverse mechanisms of action, acting as an antioxidant to counteract free radicals and prevent oxidative damage.
Glutaconic acid (CAS 1724-02-3) References
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- Vascular dysfunction as an additional pathomechanism in glutaric aciduria type I. | Mühlhausen, C., et al. 2004. J Inherit Metab Dis. 27: 829-34. PMID: 15505389
- Glutaric acid and its metabolites cause apoptosis in immature oligodendrocytes: a novel mechanism of white matter degeneration in glutaryl-CoA dehydrogenase deficiency. | Gerstner, B., et al. 2005. Pediatr Res. 57: 771-6. PMID: 15774829
- Guideline for the diagnosis and management of glutaryl-CoA dehydrogenase deficiency (glutaric aciduria type I). | Kölker, S., et al. 2007. J Inherit Metab Dis. 30: 5-22. PMID: 17203377
- Effects of structural analogues of the substrate and allosteric regulator of the human mitochondrial NAD(P)+-dependent malic enzyme. | Su, KL., et al. 2009. Bioorg Med Chem. 17: 5414-9. PMID: 19595601
- Organic acid and acylcarnitine profiles of glutaric aciduria type I. | Matsumoto, M., et al. 1990. Acta Paediatr Jpn. 32: 76-82. PMID: 2109491
- Neurotoxic effects of trans-glutaconic acid in rats. | Schuck, PF., et al. 2013. Oxid Med Cell Longev. 2013: 607610. PMID: 23606926
- Brain MRI findings as an important diagnostic clue in glutaric aciduria type 1. | Nunes, J., et al. 2013. Neuroradiol J. 26: 155-61. PMID: 23859237
- Catalytic asymmetric Tamura cycloadditions. | Manoni, F. and Connon, SJ. 2014. Angew Chem Int Ed Engl. 53: 2628-32. PMID: 24573916
- An Integrated Multi-Omic Approach to Assess Radiation Injury on the Host-Microbiome Axis. | Goudarzi, M., et al. 2016. Radiat Res. 186: 219-34. PMID: 27512828
- Proposed recommendations for diagnosing and managing individuals with glutaric aciduria type I: second revision. | Boy, N., et al. 2017. J Inherit Metab Dis. 40: 75-101. PMID: 27853989
- One-pot formation of 2,4-di- or 2,4,6-tri-olefinic monocarboxylic acids by straight chain C4-extension. | Sobotta, J., et al. 2017. Heliyon. 3: e00368. PMID: 28795165
- The outcome of 41 Late-Diagnosed Turkish GA-1 Patients: A Candidate for the Turkish NBS. | Kılavuz, S., et al. 2021. Neuropediatrics. 52: 358-369. PMID: 33578440
- The Challenge of Severe Acute Malnutrition in Inborn Errors of Metabolism: Does Medical Food Alone Suffice? | Singanamalla, B., et al. 2023. J Pediatr Genet. 12: 175-178. PMID: 37090831
- Influence of grape consumption on the human microbiome. | Dave, A., et al. 2023. Sci Rep. 13: 7706. PMID: 37173385
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Glutaconic acid, 5 g | sc-500800 | 5 g | $556.00 |