GlcNAc beta(1-2)Man alpha-1-Ethylazide

GlcNAc beta(1-2)Man alpha-1-ethylazide, a modified form of mannose, has emerged as a crucial tool in glycobiology research, specifically in the study of glycosylation processes and carbohydrate-protein interactions. The alpha-1-ethylazide group attached to the mannose residue facilitates its incorporation into glycoconjugates via metabolic glycan labeling strategies. This chemical modification allows for the selective tagging of glycoproteins and glycolipids in living cells and organisms, enabling the visualization, isolation, and identification of glycosylated biomolecules. GlcNAc beta(1-2)Man alpha-1-ethylazide has been extensively employed in conjunction with bioorthogonal chemistry techniques, such as click chemistry, to achieve site-specific labeling of glycan structures and investigate their roles in cellular processes, including protein trafficking, cell-cell interactions, and host-pathogen interactions. Moreover, this chemical probe has been instrumental in elucidating the dynamics of glycosylation in various biological systems and deciphering the functions of specific glycan epitopes in health and disease. By providing researchers with a versatile tool for studying glycobiology, GlcNAc beta(1-2)Man alpha-1-ethylazide contributes to advancing our understanding of the complex roles of carbohydrates in molecular recognition and cellular physiology.