Date published: 2026-4-24

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Gingerenone A (CAS 128700-97-0)

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Alternate Names:
(E)-1,7-bis(4-Hydroxy-3-methoxyphenyl)-4-hepten-3-one
CAS Number:
128700-97-0
Molecular Weight:
356.41
Molecular Formula:
C21H24O5
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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Gingerenone A is a diarylheptanoid found in Z. officinale (ginger). Gingerenone A belongs to a class of compounds called gingerols. It contains antifungal and antiparasitic properties. As an antioxidant, gingerenone A can help protect against oxidative stress by neutralizing free radicals, molecules that can cause cellular damage. From an agricultural perspective, understanding the biosynthesis of compounds like gingerenone A in ginger plants can inform breeding and cultivation practices aimed at enhancing the phytochemical content of ginger. This could lead to the production of ginger varieties with optimized levels of specific compounds.


Gingerenone A (CAS 128700-97-0) References

  1. [Phenolic and amide constituents from Lycianthes marlipoensis].  |  Guo, F. and Li, Y. 2011. Zhongguo Zhong Yao Za Zhi. 36: 2507-10. PMID: 22256755
  2. Anthelmintic constituents from ginger (Zingiber officinale) against Hymenolepis nana.  |  Lin, RJ., et al. 2014. Acta Trop. 140: 50-60. PMID: 25063389
  3. Identification of a Dual Inhibitor of Janus Kinase 2 (JAK2) and p70 Ribosomal S6 Kinase1 (S6K1) Pathways.  |  Byun, S., et al. 2015. J Biol Chem. 290: 23553-62. PMID: 26242912
  4. MS-Based Metabolite Profiling of Aboveground and Root Components of Zingiber mioga and Officinale.  |  Han, JS., et al. 2015. Molecules. 20: 16170-85. PMID: 26404226
  5. Gingerenone A Attenuates Monocyte-Endothelial Adhesion via Suppression of I Kappa B Kinase Phosphorylation.  |  Kim, HJ., et al. 2018. J Cell Biochem. 119: 260-268. PMID: 28513976
  6. Gingerenone A, a polyphenol present in ginger, suppresses obesity and adipose tissue inflammation in high-fat diet-fed mice.  |  Suk, S., et al. 2017. Mol Nutr Food Res. 61: PMID: 28556482
  7. Ginger (Zingiber officinale) phytochemicals-gingerenone-A and shogaol inhibit SaHPPK: molecular docking, molecular dynamics simulations and in vitro approaches.  |  Rampogu, S., et al. 2018. Ann Clin Microbiol Antimicrob. 17: 16. PMID: 29609660
  8. Gingerenone A Sensitizes the Insulin Receptor and Increases Glucose Uptake by Inhibiting the Activity of p70 S6 Kinase.  |  Chen, J., et al. 2018. Mol Nutr Food Res. 62: e1800709. PMID: 30296358
  9. In Vitro and In Vivo Antiviral Activity of Gingerenone A on Influenza A Virus Is Mediated by Targeting Janus Kinase 2.  |  Wang, J., et al. 2020. Viruses. 12: PMID: 33050000
  10. Inhibition of Escherichia coli ATP synthase by dietary ginger phenolics.  |  Hughes, T., et al. 2021. Int J Biol Macromol. 182: 2130-2143. PMID: 34087308
  11. Gingerenone A Induces Antiproliferation and Senescence of Breast Cancer Cells.  |  Yu, TJ., et al. 2022. Antioxidants (Basel). 11: PMID: 35326237
  12. Identification of gingerenone A as a novel senolytic compound.  |  Moaddel, R., et al. 2022. PLoS One. 17: e0266135. PMID: 35349590
  13. Gingerenone A Alleviates Ferroptosis in Secondary Liver Injury in Colitis Mice via Activating Nrf2-Gpx4 Signaling Pathway.  |  Chen, Y., et al. 2022. J Agric Food Chem. 70: 12525-12534. PMID: 36135333

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Gingerenone A, 250 mg

sc-490979
250 mg
$808.00

Hello, if gingerenone a opened and divided into how many degrees to keep the longest, and how long exactly

Asked by: liujie
Thank you for your question. It would be helpful if you could email us directly at asia@scbio.cn. So we can have a more interactive discussion about this and other related issues.
Answered by: Zhanglong
Date published: 2024-08-06

Hello, I purchased this drug (gingerenone A) and I see that it can be dissolved in polyethylene glycol 200, after dissolving it, should I put it in 4°, -20° or -80° to store it, how long can I keep it?

Asked by: liujie
Thank you for your question. It would be helpful if you could email us directly at asia@scbio.cn. So we can have a more interactive discussion about this and other related issues.
Answered by: Zhanglong
Date published: 2024-08-06

what is the purity % of gigerenone A

Asked by: Anuvarthini
Thank you for your question. Each lot of this chemical comes with a lot-specific Certificate of Analysis which typically describes the percent purity as well as the method used to determine the purity. You may request a lot-specific Certificate of Analysis on our website. Alternatively, please contact our Technical Service Department or reach out to your local distributor to inquire about the purity of our most recent lot.
Answered by: Tech Service 1
Date published: 2021-02-04

I am in Kannapolis, NC. How many days does the shipment take currently after I order it?

Asked by: Suren
Thank you for your question. For accurate availability, shipping and pricing information regarding our chemical products, or to receive a quote, please contact Customer Service.
Answered by: Tech Service
Date published: 2020-06-01

My name is saeideh rahmani, a Master student of Molecular cell Biology I need a smaller amount of gingerenone A(sc-490979). Are there less quantities of this product?

Asked by: rahmani
We currently advertise the smallest quantity available for purchase.
Answered by: Technical Support
Date published: 2024-04-28
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Rated 5 out of 5 by from 品质很好,物美价廉,好评试剂品质很好,实验结果很理想,五星好评!价格也和其它品牌都做了对比,比其它品牌实惠,以后还会继续购买。
Date published: 2022-07-19
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Gingerenone A is rated 5.0 out of 5 by 1.
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