Date published: 2025-12-5

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Garenoxacin-d4

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Application:
Garenoxacin-d4 is an labeled antibacterial
Molecular Weight:
430.44
Molecular Formula:
C23H16D4F2N2O4
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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Garenoxacin-d4, a deuterated derivative of Garenoxacin, is a valuable tool in scientific research, particularly in the fields of analytical chemistry and pharmacokinetics. Its isotopic substitution with deuterium enhances its stability and alters its physical and chemical properties, making it useful in various research applications. In analytical chemistry, Garenoxacin-d4 serves as an internal standard or reference compound in quantitative analysis methods such as liquid chromatography-mass spectrometry (LC-MS) or nuclear magnetic resonance (NMR) spectroscopy. By incorporating Garenoxacin-d4 into analytical workflows, researchers can accurately quantify and characterize Garenoxacin and related compounds in complex biological matrices or environmental samples. Moreover, Garenoxacin-d4 is utilized in pharmacokinetic studies to investigate the absorption, distribution, metabolism, and excretion (ADME) properties of Garenoxacin and assess its bioavailability and pharmacokinetic profile in preclinical and clinical research settings. Through its role as a stable isotopic tracer, Garenoxacin-d4 contributes to advancing our understanding of drug metabolism, drug-drug interactions, and pharmacokinetic parameters, facilitating the development of safer and more efficacious pharmaceuticals.


Garenoxacin-d4 References

  1. Comparative articular toxicity of garenoxacin, a novel quinolone antimicrobial agent, in juvenile beagle dogs.  |  Nagai, A., et al. 2002. J Toxicol Sci. 27: 219-28. PMID: 12238145
  2. Dual targeting of DNA gyrase and topoisomerase IV: target interactions of garenoxacin (BMS-284756, T-3811ME), a new desfluoroquinolone.  |  Ince, D., et al. 2002. Antimicrob Agents Chemother. 46: 3370-80. PMID: 12384338
  3. Synthesis, antibacterial activity, and toxicity of 7-(isoindolin-5-yl)-4-oxoquinoline-3-carboxylic acids. Discovery of the novel des-F(6)-quinolone antibacterial agent garenoxacin (T-3811 or BMS-284756).  |  Hayashi, K., et al. 2002. Arzneimittelforschung. 52: 903-13. PMID: 12572531

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Garenoxacin-d4, 10 mg

sc-218564
10 mg
$11000.00