Fmoc-Thr(tBu)-OH (CAS 71989-35-0)

Fmoc-Thr(tBu)-OH, also referred to as 2-Fmoc-L-threonine tert-butyl ester hydrochloride, is a derivative of an amino acid utilized in peptide synthesis and various other biochemical applications. Essentially, it is a modified version of L-threonine, a naturally occurring amino acid, with a tert-butyl ester group attached to its N-terminal end. This alteration enhances stability and makes it easier to handle during laboratory experiments. As a result, Fmoc-Thr(tBu)-OH finds extensive use in scientific research, ranging from protein and peptide synthesis to enzymatic reactions and drug delivery systems. The applications of Fmoc-Thr(tBu)-OH are diverse, spanning across various scientific realms. In protein and peptide synthesis, its stability and ease of handling make it a valuable component. Furthermore, it plays a role in enzymatic reactions, aiding in the synthesis of peptides and proteins, and even finds applications in drug delivery systems. Additionally, researchers have harnessed its potential to investigate cellular processes, such as signal transduction, and explore protein-protein interactions. Though the exact mechanism of action remains somewhat elusive, the attachment of the tert-butyl ester group to the N-terminal end is believed to empower Fmoc-Thr(tBu)-OH with a heightened stability when interacting with proteins and enzymes. This increased stability is what makes it suitable for diverse scientific research applications.