Fmoc-1-aminocyclopropane-1-carboxylic acid (CAS 126705-22-4)

Fmoc-1-aminocyclopropane-1-carboxylic acid, referred to as FMOC-CPA, emerges as a remarkable non-natural amino acid extensively employed in the synthesis of peptides, peptidomimetics, and proteins It finds utility in peptide and peptidomimetic synthesis, facilitating the creation of proteins and other biologically active molecules. Moreover, researchers leverage its potential to probe the structure and function of proteins and investigate enzyme-catalyzed reactions. The unique attributes of Fmoc-1-aminocyclopropane-1-carboxylic acid underscore its significance for scientists and researchers. The fluorenyl group, functioning as an electron-donating entity, enables the formation of a stable covalent bond between Fmoc-1-aminocyclopropane-1-carboxylic acid and the peptide. Additionally, the methoxycarbonyl group, also serving as an electron-donating group, contributes to stabilizing the bond. Furthermore, the cyclopropanation of the intermediate product imparts added stability to the resulting bond, enhancing the overall efficacy of Fmoc-1-aminocyclopropane-1-carboxylic acid as a research tool.