FIV dUTPase Antibody (DU13): sc-73576

FIV dUTPase Antibody (DU13) is a mouse monoclonal IgG1 antibody that detects the FIV dUTPase protein of FIV origin by western blotting (WB), immunofluorescence (IF), and immunohistochemistry. Anti-FIV dUTPase antibody (DU13) is available as the non-conjugated format. Feline immunodeficiency virus (FIV), a lentivirus closely related to human immunodeficiency virus (HIV), poses significant health risks to domestic cats by compromising their immune systems. FIV dUTPase (DU13) antibody recognizes a protein that plays a critical role in viral replication by catalyzing the conversion of deoxyuridine triphosphate (dUTP) to deoxyuridine monophosphate (dUMP), which is essential for the synthesis of deoxythymidine triphosphate (dTTP). This enzymatic activity is vital for maintaining a low concentration of dUTP within the cell, thereby preventing the incorporation of uracil into DNA, which can lead to mutations and instability in the viral genome. By ensuring accurate DNA replication, FIV dUTPase contributes to the stability of the virus and its ability to infect host cells effectively. A reduction in the function of FIV dUTPase can compromise viral replication and may hinder the progression of FIV infection in cats, making FIV dUTPase a potential target for therapeutic interventions.

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FIV dUTPase Antibody (DU13) References:

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