Molecular structure of Fenvalerate, CAS Number: 51630-58-1
Fenvalerate (CAS 51630-58-1)
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Application:
Fenvalerate is a potent inhibitor of calcineurin with suggested activity at GABA receptors and other neuronal activity
CAS Number:
51630-58-1
Purity:
≥98%
Molecular Weight:
419.9
Molecular Formula:
C25H22ClNO3
Supplemental Information:
This is classified as a Dangerous Good for transport and may be subject to additional shipping charges.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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SDS & Certificate of Analysis
Fenvalerate is a synthetic compound that modulates sodium channels in the nerve cell membrane and also acts as a potent PP2B-Aα (calcineurin) inhibitor IC50~20 nM; however, serious doubts have been raised about the efficacy of this inhibitor. This compound has also been shown to have possible GABA receptor activity, yielding anxiogenic effects in rats.
Fenvalerate (CAS 51630-58-1) References
- Possible anxiogenic effects of fenvalerate, a type II pyrethroid pesticide, in rats. | De Souza Spinosa, H., et al. 1999. Physiol Behav. 67: 611-5. PMID: 10549901
- Specific inhibition of calcineurin by type II synthetic pyrethroid insecticides. | Enan, E. and Matsumura, F. 1992. Biochem Pharmacol. 43: 1777-84. PMID: 1315545
- Nerve membrane Na+ channels as targets of insecticides. | Narahashi, T. 1992. Trends Pharmacol Sci. 13: 236-41. PMID: 1321523
- Effects of Thiamethoxam and Fenvalerate Residue Levels on Light-Stable Isotopes of Leafy Vegetables. | Qi, F., et al. 2023. Foods. 12: PMID: 37509747
- Machine learning-assisted fluorescence sensor array for qualitative and quantitative analysis of pyrethroid pesticides. | Li, M., et al. 2024. Food Chem. 433: 137368. PMID: 37688823
- Curcumin protects against fenvalerate-induced neurotoxicity in zebrafish (Danio rerio) larvae through inhibition of oxidative stress. | Zhu, J., et al. 2023. Ecotoxicol Environ Saf. 264: 115484. PMID: 37716069
- Identification and characterization of both cis- and trans-regulators mediating fenvalerate-induced expression of CYP6B7 in Helicoverpa armigera. | Huang, Y., et al. 2024. Int J Biol Macromol. 258: 128995. PMID: 38159702
- Late gestational exposure to fenvalerate impacts ovarian reserve in neonatal mice via YTHDF2-mediated P-body assembly. | He, F., et al. 2024. Sci Total Environ. 925: 171790. PMID: 38508253
- SlCarE054 in Spodoptera litura (Lepidoptera: Noctuidae) showed direct metabolic activity to β-cypermethrin with stereoselectivity. | Xu, L., et al. 2024. Bull Entomol Res. 1-9. PMID: 38708572
- Prenatal exposure to fenvalerate causes depressive-like behavior in adulthood by inhibiting brain-derived 5-HT synthesis. | Zhu, HM., et al. 2024. Environ Pollut. 352: 124137. PMID: 38740245
- Confirmation of the steroid hormone receptor-mediated endocrine disrupting potential of fenvalerate following the Organization for Economic Cooperation and Development test guidelines, and its estrogen receptor α-dependent effects on lipid accumulation. | Jeong, DH., et al. 2024. Comp Biochem Physiol C Toxicol Pharmacol. 283: 109955. PMID: 38844189
- Functional study on candidate regulators mediating the expression of CYP6B7 induced by fenvalerate in a susceptible strain of Helicoverpa armigera. | Huang, Y., et al. 2024. Pestic Biochem Physiol. 202: 105918. PMID: 38879320
- [Social history taking and social therapy in psychiatry]. | Böcker, F. 1977. Med Welt. 28: 1678-81. PMID: 927133
Inhibitor of:
CaMKIγ, CCDC25, Olfr381, Olfr584, p55 CDC, PP2B, and STEP.Activator of:
Olfr324.Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Fenvalerate, 25 mg | sc-24014 | 25 mg | $78.00 | |||
Fenvalerate, 100 mg | sc-24014A | 100 mg | $226.00 |