Molecular structure of Fenclofenac, CAS Number: 34645-84-6
Fenclofenac (CAS 34645-84-6)
Alternate Names:
2-(2,4-Dichlorophenoxy)benzeneacetic Acid, Fenclofenac; Flenac; R 67408; RX 67408; [o-(2,4-Dichlorophenoxy)phenyl]acetic Acid
CAS Number:
34645-84-6
Molecular Weight:
297.13
Molecular Formula:
C14H10Cl2O3
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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Fenclofenac functions as a potent inhibitor of cyclooxygenase, targeting the COX-1 and COX-2 enzymes. By inhibiting these enzymes, fenclofenac disrupts the conversion of arachidonic acid into prostaglandins. Fenclofenac′s mechanism of action involves binding to the active site of the COX enzymes, preventing the formation of prostaglandins and ultimately reducing the inflammatory response. Fenclofenac may exhibit antioxidant properties, further contributing to its anti-inflammatory effects. Its ability to modulate the production of prostaglandins and mitigate oxidative stress makes fenclofenac valuable for investigating the molecular pathways involved in inflammation and pain.
Fenclofenac (CAS 34645-84-6) References
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- Effects of non-narcotic analgesics on the liver. | Prescott, LF. 1986. Drugs. 32 Suppl 4: 129-47. PMID: 3552580
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- Effect of fenclofenac on prostaglandin production in carageenin air bleb exudates in rats. | Atkinson, DC. and Leach, EC. 1978. Agents Actions. 8: 263-7. PMID: 665437
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- Species differences in the metabolism and excretion of fenclofenac. | Greenslade, D., et al. 1980. Xenobiotica. 10: 753-60. PMID: 7456491
- The effect of fenclofenac on the regeneration of lymphocytes in rats following total body irradiation. | Spiers, EM., et al. 1993. Int J Immunopharmacol. 15: 865-9. PMID: 7902830
- Drug effects on triiodothyronine uptake by rat anterior pituitary cells in vitro. | Lim, CF., et al. 1996. Exp Clin Endocrinol Diabetes. 104: 151-7. PMID: 8740939
- Anti-inflammatory and related properties of 2-(2,4-dichlorophenoxy)phenylacetic acid (fenclofenac). | Atkinson, DC. and Leach, EC. 1976. Agents Actions. 6: 657-66. PMID: 970297
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Fenclofenac, 500 mg | sc-495918 | 500 mg | $401.00 |