Molecular structure of Fasciculatin, CAS Number: 37905-12-7
Fasciculatin (CAS 37905-12-7)
Application:
Fasciculatin is a novel furanosesterterpene secondary marine metabolite
CAS Number:
37905-12-7
Molecular Weight:
398.54
Molecular Formula:
C25H34O4
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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SDS & Certificate of Analysis
Fasciculatin is a furanosesterterpene secondary marine metabolite isolated from marine sponges and discovered in Aplysilla sulfurea Schulze. Fasciculatin isolated from Ircinia variabilis displayed moderate cytotoxicity against cancer cell lines MCF-7, NCI-H460 and SF-268 with respective IC50 values of 47.11 ± 0.93, 64.49 ± 0.84 and 72.45 ± 2.19. In the same study the compound displayed no activity towards the proliferation of human lymphocytes.
Fasciculatin (CAS 37905-12-7) References
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- Fasciculatin, a novel sesterterpene from the sponge Ircinia fasciculata. | Cafieri, F., et al. 1972. Tetrahedron. 28.6: 1579-1583.
- The occurrence, structure elucidation and biosynthesis of the sesterterpenes. | Cordell, Geoffrey A. 1974. Phytochemistry. 13.11: 2343-2364.
- Palinurin, a new linear sesterterpene from a marine sponge. | Alfano, G., et al. 1979. Experientia. 35.9: 1136-1137.
- Defense allomones of some marine mollusks. | Schulte, Gary R. and Paul J. Scheuer. 1982. Tetrahedron. 38.13: 1857-1863.
- The chemical defense of nudibranch molluscs: Structure, biosynthetic origin and defensive properties of terpenoids from the dorid nudibranch dendrodoris grandiflora. | Cimino, Guido, et al. 1985. Tetrahedron. 41.6: 1093-1100.
- Morphological and chemical camouflage of the Mediterranean nudibranch Discodoris indecora on the sponges Ircinia variabilis and Ircinia fasciculata. | Marin, A., et al. 1997. Journal of Molluscan Studies. 63.3: 431-439.
- A new marine metabolite from Isis hippuris and a furanosesterterpene from Aplysilla sulfurea. | Chang, Yao-To, et al. 2003. The Chinese Pharmaceutical Journal. 55.2: 129-133.
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| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Fasciculatin, 1 mg | sc-202607 | 1 mg | $109.00 |