Esomeprazole-d3 Sodium Salt (CAS 119141-88-7 unlabeled)

Esomeprazole-d3 Sodium Salt is a deuterated version of esomeprazole, a proton pump inhibitor (PPI) extensively used in research applications to explore the mechanisms of gastric acid secretion and its regulation. The incorporation of deuterium atoms (d3) in place of hydrogen enhances the molecule′s metabolic stability, making it an invaluable tool for pharmacokinetic and pharmacodynamic studies. By specifically targeting the H+/K+ ATPase enzyme system in the parietal cells of the stomach, this compound effectively suppresses the final step in acid production, thereby reducing gastric acidity. This characteristic action is for researchers studying the pathophysiology of acid-related disorders and the molecular intricacies of acid secretion control. In laboratory environments, Esomeprazole-d3 Sodium Salt serves not only as a model compound to investigate the fundamental aspects of proton pump inhibitor activity but also as a marker in mass spectrometry-based analyses to discern metabolic pathways and enzyme interactions, providing insights into the dynamics of acid inhibition and the broader implications for understanding gastrointestinal disorders at the molecular level.