Molecular structure of Epibestatin hydrochloride, CAS Number: 100992-60-7
Epibestatin hydrochloride (CAS 100992-60-7)
Application:
Epibestatin hydrochloride is a diastereoepimer of aminopeptidase inhibitor bestatin
CAS Number:
100992-60-7
Molecular Weight:
344.83
Molecular Formula:
C16H24N2O4•HCl
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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Description
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SDS & Certificate of Analysis
Epibestatin hydrochloride is a small molecule inhibitor that functions by targeting and inhibiting the activity of the integrin α5β1. This inhibition prevents the binding of fibronectin to the integrin, thereby disrupting cell adhesion and migration processes. By interfering with integrin-mediated signaling pathways, Epibestatin hydrochloride effectively modulates cellular functions such as proliferation, survival, and differentiation. At the molecular level, Epibestatin hydrochloride acts as a competitive antagonist, binding to the integrin receptor and blocking its interaction with fibronectin. This disruption of integrin function has implications for various cellular processes.
Epibestatin hydrochloride (CAS 100992-60-7) References
- Interferon-regulatory factor-1 is critical for tamoxifen-mediated apoptosis in human mammary epithelial cells. | Bowie, ML., et al. 2004. Oncogene. 23: 8743-55. PMID: 15467738
- CREB-binding protein regulates apoptosis and growth of HMECs grown in reconstituted ECM via laminin-5. | Dietze, EC., et al. 2005. J Cell Sci. 118: 5005-22. PMID: 16219677
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Epibestatin hydrochloride, 1 mg | sc-214966A | 1 mg | $260.00 | |||
Epibestatin hydrochloride, 5 mg | sc-214966 | 5 mg | $813.00 |