Date published: 2025-11-30

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Enalaprilat-d5 Sodium Salt (CAS 1356922-29-6)

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Alternate Names:
Enalaprilic Acid-d5
Application:
Enalaprilat-d5 Sodium Salt is a labeled metabolite of Enalapril
CAS Number:
1356922-29-6
Molecular Weight:
375.41
Molecular Formula:
C18H18D5N2NaO5
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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Enalaprilat-d5 Sodium Salt is a deuterated form of enalaprilat primarily utilized in research focused on elucidating the metabolic pathways and kinetics of the parent compound. In studies, it acts as a stable isotopic label that allows scientists to track the distribution and breakdown of enalaprilat without interference from the body′s natural isotopes. This compound is also employed as an internal standard in mass spectrometry to ensure accurate quantification, given its nearly identical chemical behavior to non-deuterated enalaprilat. Its presence in experimental setups facilitates the understanding of the role and behavior of enalaprilat in various biological systems. Researchers often use Enalaprilat-d5 Sodium Salt in analytical chemistry to improve the precision of their measurements and to better understand the enzymatic processes it may participate in.


Enalaprilat-d5 Sodium Salt (CAS 1356922-29-6) References

  1. The direct effects of the angiotensin-converting enzyme inhibitors, zofenoprilat and enalaprilat, on isolated human pancreatic islets.  |  Lupi, R., et al. 2006. Eur J Endocrinol. 154: 355-61. PMID: 16452552
  2. Spironolactone and enalapril differentially up-regulate the expression of VEGF and heme oxygenase-1 in the neonatal rat kidney.  |  Yim, HE., et al. 2011. Pediatr Res. 69: 378-83. PMID: 21263376
  3. [Effects of enalapril on NF-kappaB expression in mucus hypersecretion rats induced by acrolein exposure].  |  Zhang, YH., et al. 2010. Sichuan Da Xue Xue Bao Yi Xue Ban. 41: 998-1002. PMID: 21265102
  4. [Effects of enalapril on IL-1beta, IL-6 expression in rat lung exposure to acrolein].  |  Wang, SL., et al. 2010. Sichuan Da Xue Xue Bao Yi Xue Ban. 41: 1003-7, 1038. PMID: 21265103
  5. Clinical pharmacokinetics of the newer ACE inhibitors. A review.  |  Kelly, JG. and O'Malley, K. 1990. Clin Pharmacokinet. 19: 177-96. PMID: 2203579
  6. Enalaprilat, an intravenous angiotensin-converting enzyme inhibitor, in hypertensive crises.  |  DiPette, DJ., et al. 1985. Clin Pharmacol Ther. 38: 199-204. PMID: 2990798
  7. The physiological disposition and metabolism of enalapril maleate in laboratory animals.  |  Tocco, DJ., et al. 1982. Drug Metab Dispos. 10: 15-9. PMID: 6124377
  8. Tissue angiotensin converting enzyme inhibition as an index of the disposition of enalapril (MK-421) and metabolite MK-422.  |  Cohen, ML., et al. 1983. J Pharmacol Exp Ther. 226: 192-6. PMID: 6306224
  9. Simultaneous Determination of Carvedilol, Enalaprilat, and Perindoprilat in Human Plasma Using LC–MS/MS and Its Application to a Pharmacokinetic Pilot Study  |  A Joubert, T Kellermann, A Joubert, M van der Merwe. 2022. Chromatographia. 85: 455–468.

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Enalaprilat-d5 Sodium Salt, 1 mg

sc-218306
1 mg
$444.00